| known also as: |
C21, DC42, IRA1, TBL1-related protein 1, transducin (beta)-like 1 X-linked receptor 1), Anti-TBLR1 (TBL1XR1 |
| known also as: |
C21, DC42, IRA1, TBL1-related protein 1, transducin (beta)-like 1 X-linked receptor 1), TBLR1 (TBL1XR1 |
| known also as: |
C21, DC42, IRA1, TBL1-related protein 1, transducin (beta)-like 1 X-linked receptor 1), TBLR1 (TBL1XR1 |
| known also as: |
TBLR1 |
| known also as: |
C21, DC42, IRA1, TBL1-related protein 1, transducin (beta)-like 1 X-linked receptor 1), Anti -TBLR1 (TBL1XR1 |
| Other names: |
F-box-like/WD repeat-containing protein TBL1XR1, F-box-like/WD repeat-containing protein TBL1XR1, Nuclear receptor corepressor/HDAC3 complex subunit TBLR1, OTTHUMP00000211531, OTTHUMP00000211535, TBL1-related protein 1, TBL1-related protein 1, Transducin beta-like 1X-related protein 1, nuclear receptor co-repressor/HDAC3 complex subunit, nuclear receptor corepressor/HDAC3 complex subunit TBLR1, transducin (beta)-like 1 X-linked receptor 1, transducin beta-like 1X-related protein 1, Transducin (beta)-like 1 X-linked receptor 1 |
| Other gene names: |
C21, DC42, FLJ12894, IRA1, IRA1, TBL1XR1, TBLR1, TBLR1, TBL1XR1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Mouse, Rat, Human |
| Specificity and cross-reactivity: |
Although TBLR1 is thought to be a core component of both the N-CoR and SMRT complexes, HDAC3 is the main HDAC that associates with N-CoR and SMRT complexes, N-CoR and SMRT each exist in large protein complexes, TBLR1 is a WD-40 repeat protein that also associates with N-CoR and SMRT complexes, The nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid homone receptors (SMRT) play a role in diverse transcriptional repression pathways, and are thought to mediate repression, and its presence is thought to be essential for repression, at least in part, by their ability to recruit histone deacetylases to generate repressive chromatin, its role in these complexes remains to be elucidated, Chromatin organization plays a fundamental role in regulating transcription in eukaryotic cells |
| Purification method: |
Purified |
| Form/Appearance: |
0, 0, 05% sodium azide, 2% gelatin, Supplied as a liquid in PBS |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Freeze productone should be stored at -20 degrees Celsius, Further dilutions can be made in assay buffer, aliquot and add glycerol (40-50%), centrifuge the original vial after thawing and prior to removing the cap, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Western Blot (WB) |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
C21, DC42, IRA1, TBL1-related protein 1, transducin (beta) like 1 X-linked receptor 1), TBLR1 (TBL1XR1 |
| Short name: |
C21, DC42, IRA1, TBL1-related protein 1, transducin (beta)-like 1 X-linked receptor 1), TBLR1 (TBL1XR1 |
| Alternative name: |
C21, DC42, IRA1, TBL1-related protein 1, transducin (b)-like 1 X-linked receptor 1), TBLR1 (TBL1XR1 |
| Identity: |
29529 |
| Gene: |
TBL1XR1 |
More about : TBL1XR1 |
| Long gene name: |
transducin beta like 1 X-linked receptor 1 |
| Synonyms gene name: |
transducin (beta)-like 1X-linked receptor 1 |
| Synonyms: |
IRA1 FLJ12894 TBLR1 C21 DC42 |
| Locus: |
3q26, 32 |
| Discovery year: |
2004-08-09 |
| GenBank acession: |
AK022956 |
| Entrez gene record: |
79718 |
| Pubmed identfication: |
11063877 11931768 |
| RefSeq identity: |
NM_024665 |
| Classification: |
WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000157140 |