| Also known as: |
c-erbB-2/HER-2 |
| Other names: |
MLN 19, Metastatic lymph node gene 19 protein, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, c-erb B2/neu protein, herstatin, metastatic lymph node gene 19 protein, neuro/glioblastoma derived oncogene homolog (avian), neuroblastoma/glioblastoma derived oncogene homolog, p185erbB2, p185erbB2, proto-oncogene Neu, proto-oncogene c-ErbB-2, receptor tyrosine-protein kinase erbB-2, tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, receptor tyrosine-protein kinase erbB-2 isoform b |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
c-erbB-2/HER-2 |
| Other gene names: |
CD340, ERBB2, HER-2, HER-2/neu, HER2, HER2, MLN 19, MLN 19, MLN19, NEU, NEU, NGL, NGL, TKR1, ERBB2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
Rabbit IgG |
| Clone: |
SP3 |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, <, /b>, /b>, Dog, Expected from sequence similarity: <, Human (Homo sapiens) <, Tested: <, b>, b> |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Form/Appearance: |
1 ml rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7, 1% sodium azide, 5 with less than 0 |
| Storage and shipping: |
DO NOT FREEZE, Do not use the reagent beyond the expiration date, The user must validate any other storage conditions, When properly stored, the reagent is stable to the date indicated on the label, Store the antibody ats should be kept in the range of 1-7 degrees Celsius |
| Tested applications:: |
Immunohistochemistry (IHC) (Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target: |
c-erbB2 MAb SP3) |
| Short name: |
Anti- c-erbB2 MAb (Clone SP3) |
| Species: |
Humans, Human |
| Alternative name: |
neuro/glioblastoma derived oncogene homolog (avian) monoclonal (clonality Sp3 transcription factor), sapiens c-v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, antibody to-H |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0016605 and PML body and cellular component this GO :0017053 and transcriptional repressor complex and cellular component this GO :0030183 and B cell differentiation and biological process this GO :0030217 and T cell differentiation and biological process this GO :0030218 and erythrocyte differentiation and biological process this GO :0030219 and megakaryocyte differentiation and biological process this GO :0030224 and monocyte differentiation and biological process this GO :0030324 and lung development and biological process this GO :0030851 and granulocyte differentiation and biological process this GO :0043353 and enucleate erythrocyte differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048596 and embryonic camera-type eye morphogenesis and biological process this GO :0048706 and embryonic skeletal system development and biological process this GO :0060136 and embryonic process involved in female pregnancy and biological process this GO :0060216 and definitive hemopoiesis and biological process, SP3 and IDBG-640536 and ENSBTAG00000000176 and 540766, SP3 and IDBG-75293 and ENSG00000172845 and 6670, SPR2, Sp3 and IDBG-179756 and ENSMUSG00000027109 and 20687, metal ion binding, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0000987 and core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001503 and ossification and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001779 and natural killer cell differentiation and biological process this GO :0001829 and trophectodermal cell differentiation and biological process this GO :0001889 and liver development and biological process this GO :0001892 and embryonic placenta development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0000987 : core promoter proximal region sequence-specific DNA binding and also this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0005515 : protein binding and also this GO :0046872 : metal ion binding, this GO :0000987 : core promoter proximal region sequence-specific DNA binding, this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003690 : double-stranded DNA binding, this GO :0005515 : protein binding, this GO :0046872 : metal ion binding, Sp3 transcription factor |
| Identity: |
11208 |
| Gene: |
SP3 |
More about : SP3 |
| Long gene name: |
Sp3 transcription factor |
| Synonyms: |
SPR-2 |
| Locus: |
2q31, 1 |
| Discovery year: |
1993-02-10 |
| GenBank acession: |
M97191 |
| Entrez gene record: |
6670 |
| Pubmed identfication: |
1341900 1454515 |
| RefSeq identity: |
NM_003111 |
| Classification: |
Sp transcription factors Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000132333 |