| known also as: |
Anti-Goat Polyclonal to Human IGF-II / IGF2 |
| known also as: |
Caprine PAb to Human IGF-II / IGF2 |
| known also as: |
Caprinae Polyclonal to Homo sapiens IGF-II / IGF2 |
| known also as: |
IGF-II / IGF2 |
| known also as: |
C11orf43, Human IGF-II, IGF-II, IGF2, IGF2, Insulin-like growth factor II, PP9974, Somatomedin-A, Anti-IGF-II / IGF2 Antibody (aa81-93) IHC-plus |
| Other names: |
Insulin-like growth factor II, Insulin-like growth factor II Ala-25 Del, Preptin, Somatomedin-ACleaved into the following 3 chains:Insulin-like growth factor II, insulin-like growth factor 2, insulin-like growth factor 2 (somatomedin A), insulin-like growth factor II, insulin-like growth factor type 2, insulin-like growth factor II isoform 1 preproprotein |
| Gene name: |
IGF-II |
| Gene name synonims: |
IGF2 |
| Other gene names: |
C11orf43, IGF-II, IGF-II, IGF2, PP9974, IGF2 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Bovine, Dog, Gorilla, Guinea pig, Horse, Human, Monkey, Mouse, Orangutan, Rabbit, Rat, Gibbon |
| Specificity and cross-reactivity: |
NP_001007140, NP_001121070, Reported variants represent identical protein: NP_000603, This antibody is expected to recognize both reported isoforms (NP_000603, 1, 1, 1), 2, Human IGF2 |
| Purification method: |
Immunoaffinity Purified |
| Form/Appearance: |
0, 0, pH 7, 02% sodium azide, 3, 5% BSA, Tris-buffered saline |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Minimize freezing and thawing, productone should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested for:: |
ELISA (EIA), Immunohistochemistry (IHC - Paraffin) |
| Description: |
IGF-1 acts via specific receptor, IGF-1R, IGF-II, Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver, Raf/Ras and PI3K cascades, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells, IGF-I |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°, humans , ssp |
| Latin name: |
Capra aegagrus hircus |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
II / IGF2 |
| Short name: |
Goat Polyclonal IGF-II / IGF2 Antibody |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , antibodies against human proteins, antibodies for, each identifying a different , goats, igfs, whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Host: |
It are very good secondary antibodies that are affinity purified and have a good affinity themselves too, Often KLH is coupled to the antigen so anti KLH can be present in the vial, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection, Goat |
| Species: |
Goats, Humans, Human |
| Alternative name: |
sapiens IGF-II / insulin-like growth factor 2 (somatomedin A) (Antibody to), caprine polyclonal to H |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
C11orf43 and IGF-II and PP9974, DNA-templated and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007565 and female pregnancy and biological process this GO :0007596 and blood coagulation and biological process this GO :0007613 and memory and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0009314 and response to radiation and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0030168 and platelet activation and biological process this GO :0030546 and receptor activator activity and molecular function this GO :0031017 and exocrine pancreas development and biological process this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0031667 and response to nutrient levels and biological process this GO :0032355 and response to estradiol and biological process this GO :0035094 and response to nicotine and biological process this GO :0038028 and insulin receptor signaling pathway via phosphatidylinositol 3-kinase and biological process this GO :0042060 and wound healing and biological process this GO :0042104 and positive regulation of activated T cell proliferation and biological process this GO :0042493 and response to drug and biological process this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043539 and protein serine/threonine kinase activator activity and molecular function this GO :0044267 and cellular protein metabolic process and biological process this GO :0045471 and response to ethanol and biological process this GO :0045725 and positive regulation of glycogen biosynthetic process and biological process this GO :0045840 and positive regulation of mitosis and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046628 and positive regulation of insulin receptor signaling pathway and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0051146 and striated muscle cell differentiation and biological process this GO :0051781 and positive regulation of cell division and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071902 and positive regulation of protein serine/threonine kinase activity and biological process this GO :0090031 and positive regulation of steroid hormone biosynthetic process and biological process this GO :2000273 and positive regulation of receptor activity and biological process this GO :2000467 and positive regulation of glycogen (starch) synthase activity and biological process, Extracellular, IGF2 and IDBG-20829 and ENSG00000167244 and 3481, IGF2 and IDBG-645244 and ENSBTAG00000013066 and 281240, Igf2 and IDBG-212623 and ENSMUSG00000048583 and 16002, protein serine/threonine kinase activator activity, this GO :0001501 and skeletal system development and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002576 and platelet degranulation and biological process this GO :0005158 and insulin receptor binding and molecular function this GO :0005159 and insulin-like growth factor receptor binding and molecular function this GO :0005179 and hormone activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006006 and glucose metabolic process and biological process this GO :0006349 and regulation of gene expression by genetic imprinting and biological process this GO :0006355 and regulation of transcription, this GO :0005158 : insulin receptor binding, this GO :0005158 : insulin receptor binding and also this GO :0005159 : insulin-like growth factor receptor binding and also this GO :0005179 : hormone activity and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0030546 : receptor activator activity and also this GO :0043539 : protein serine/threonine kinase activator activity, this GO :0005159 : insulin-like growth factor receptor binding, this GO :0005179 : hormone activity, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0030546 : receptor activator activity, this GO :0043539 : protein serine/threonine kinase activator activity, insulin-like growth factor 2 (somatomedin A) |
| Identity: |
5466 |
| Gene: |
IGF2 |
More about : IGF2 |
| Long gene name: |
insulin like growth factor 2 |
| Synonyms gene: |
C11orf43 |
| Synonyms gene name: |
chromosome 11 open reading frame 43 insulin-like growth factor 2 |
| Synonyms: |
FLJ44734 IGF-II |
| Synonyms name: |
somatomedin A preptin |
| Locus: |
11p15, 5 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M29645 AK025719 |
| Entrez gene record: |
3481 |
| Pubmed identfication: |
2450353 3167054 |
| RefSeq identity: |
NM_000612 |
| Havana BLAST/BLAT: |
OTTHUMG00000009395 |
| Locus Specific Databases: |
LOVD - Leiden Open Variation Database LRG_1031 |