| known also as: |
Anti-Goat Polyclonal to Human PYCARD / ASC |
| known also as: |
Caprine PAb to Human PYCARD / ASC |
| known also as: |
Caprinae Polyclonal to Homo sapiens PYCARD / ASC |
| known also as: |
PYCARD / ASC |
| known also as: |
ASC, ASC, CARD5, HASC, Human PYCARD, PYCARD, PYD and CARD domain containing, TMS, TMS-1, TMS1, Anti-PYCARD / ASC Antibody (C-Terminus) IHC-plus |
| Other names: |
Apoptosis-associated speck-like protein containing a CARD, Caspase recruitment domain-containing protein 5, PYD and CARD domain containing, PYD and CARD domain-containing protein, Target of methylation-induced silencing 1, apoptosis-associated speck-like protein containing a CARD, caspase recruitment domain-containing protein 5, target of methylation-induced silencing 1, apoptosis-associated speck-like protein containing a CARD isoform a |
| Gene name: |
PYCARD |
| Gene name synonims: |
ASC |
| Other gene names: |
ASC, ASC, CARD5, CARD5, PYCARD, TMS, TMS-1, TMS1, TMS1, hASC, PYCARD |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Gorilla, Human <, /b>, Gibbon, Monkey (at least 90% immunogen sequence identity), Predicted Reactivity: <, b> |
| Specificity and cross-reactivity: |
This antibody is expected to recognise all reported Human isoforms according to NP_037390, 1, 2 and NP_660183, Human PYCARD |
| Purification method: |
Immunoaffinity Purified |
| Form/Appearance: |
0, 0, pH 7, 02% sodium azide, 3, 5% BSA, Tris-buffered saline |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Minimize freezing and thawing, productone should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested for:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°, humans , ssp |
| Latin name: |
Capra aegagrus hircus |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PYCARD / ASC |
| Short name: |
Goat Polyclonal PYCARD / ASC Antibody |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , antibodies against human proteins, antibodies for, each identifying a different , goats, whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Host: |
It are very good secondary antibodies that are affinity purified and have a good affinity themselves too, Often KLH is coupled to the antigen so anti KLH can be present in the vial, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection, Goat |
| Species: |
Goats, Humans, Human |
| Alternative name: |
sapiens PYD and CARD domain containing / ASC (Antibody to), caprine polyclonal to H |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
PYCARD and IDBG-28012 and ENSG00000103490 and 29108, PYCARD and IDBG-639579 and ENSBTAG00000020535 and 282846, Pycard and IDBG-210514 and ENSMUSG00000030793 and 66824, leucine rich repeat containing receptor signaling pathway and biological process this GO :0042104 and positive regulation of activated T cell proliferation and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0044351 and macropinocytosis and biological process this GO :0045087 and innate immune response and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0050829 and defense response to Gram-negative bacterium and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051607 and defense response to virus and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071901 and negative regulation of protein serine/threonine kinase activity and biological process this GO :0072332 and intrinsic apoptotic signaling pathway by p53 class mediator and biological process this GO :0072558 and NLRP1 inflammasome complex and cellular component this GO :0072559 and NLRP3 inflammasome complex and cellular component this GO :0090197 and positive regulation of chemokine secretion and biological process this GO :0090200 and positive regulation of release of cytochrome c from mitochondria and biological process this GO :0097169 and AIM2 inflammasome complex and cellular component this GO :2000406 and positive regulation of T cell migration and biological process this GO :2000484 and positive regulation of interleukin-8 secretion and biological process this GO :2000778 and positive regulation of interleukin-6 secretion and biological process this GO :2001056 and positive regulation of cysteine-type endopeptidase activity and biological process this GO :2001181 and positive regulation of interleukin-10 secretion and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001242 and regulation of intrinsic apoptotic signaling pathway and biological process, nuclei, protein homodimerization activity, this GO :0001773 and myeloid dendritic cell activation and biological process this GO :0002218 and activation of innate immune response and biological process this GO :0002277 and myeloid dendritic cell activation involved in immune response and biological process this GO :0002588 and positive regulation of antigen processing and presentation of peptide antigen via MHC class II and biological process this GO :0002821 and positive regulation of adaptive immune response and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008385 and IkappaB kinase complex and cellular component this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0010803 and regulation of tumor necrosis factor-mediated signaling pathway and biological process this GO :0030838 and positive regulation of actin filament polymerization and biological process this GO :0031647 and regulation of protein stability and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032090 and Pyrin domain binding and molecular function this GO :0032688 and negative regulation of interferon-beta production and biological process this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0035872 and nucleotide-binding domain, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process and also this GO :0032090 : Pyrin domain binding and also this GO :0042803 : protein homodimerization activity, this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0032090 : Pyrin domain binding, this GO :0042803 : protein homodimerization activity, PYD and CARD domain containing |
| Identity: |
16608 |
| Gene: |
PYCARD |
More about : PYCARD |
| Long gene name: |
PYD and CARD domain containing |
| Synonyms: |
TMS-1 CARD5 ASC |
| Locus: |
16p11, 2 |
| Discovery year: |
2004-06-25 |
| GenBank acession: |
AB023416 |
| Entrez gene record: |
29108 |
| RefSeq identity: |
NM_013258 |
| Classification: |
Caspase recruitment domain containing Pyrin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000176753 |