| known also as: |
Anti-Goat Polyclonal to Human SERPINE1 / PAI-1 |
| known also as: |
Caprine PAb to Human SERPINE1 / PAI-1 |
| known also as: |
Caprinae Polyclonal to Homo sapiens SERPINE1 / PAI-1 |
| known also as: |
SERPINE1 / PAI-1 |
| known also as: |
Human SERPINE1, PAI-1, PAI-1, PAI1, PLANH1, SERPINE1, Serpin E1, Anti-SERPINE1 / PAI-1 Antibody (Internal) IHC-plus |
| Other names: |
Endothelial plasminogen activator inhibitor, Plasminogen activator inhibitor 1, Serpin E1, clade E (nexin, clade E (nexin, endothelial plasminogen activator inhibitor, member 1, member 1, plasminogen activator inhibitor 1, plasminogen activator inhibitor type 1), plasminogen activator inhibitor type 1), serine (or cysteine) proteinase inhibitor, serpin E1, serpin peptidase inhibitor, plasminogen activator inhibitor 1 |
| Gene name: |
SERPINE1 |
| Gene name synonims: |
PAI-1 |
| Other gene names: |
PAI, PAI, PAI-1, PAI-1, PAI1, PAI1, PLANH1, PLANH1, SERPINE1, SERPINE1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human <, Monkey (at least 90% immunogen sequence identity), /b>, Gibbon, Gorilla, Predicted Reactivity: <, b> |
| Specificity and cross-reactivity: |
This antibody is expected to recognise both reported isoforms, Human SERPINE1 / PAI-1 |
| Purification method: |
Immunoaffinity Purified |
| Form/Appearance: |
0, 0, pH 7, 02% sodium azide, 3, 5% BSA, Tris-buffered saline |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Minimize freezing and thawing, productone should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested for:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°, humans , ssp |
| Latin name: |
Capra aegagrus hircus |
| Gene: |
SERPINE1 |
More about : SERPINE1 |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SERPINE1 / PAI-1 |
| Short name: |
Goat Polyclonal SERPINE1 / PAI-1 Antibody |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , antibodies against human proteins, antibodies for, each identifying a different , goats, whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Host: |
It are very good secondary antibodies that are affinity purified and have a good affinity themselves too, Often KLH is coupled to the antigen so anti KLH can be present in the vial, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection, Goat |
| Species: |
Goats, Humans, Human |
| Alternative name: |
clade E (nexin, member 1 / PAI-1 (Antibody to), plasminogen activator inhibitor classification 1), sapiens serpin peptidase inhibitor, caprine polyclonal to H |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0010467 and gene expression and biological process this GO :0010469 and regulation of receptor activity and biological process this GO :0010757 and negative regulation of plasminogen activation and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0014912 and negative regulation of smooth muscle cell migration and biological process this GO :0030168 and platelet activation and biological process this GO :0030194 and positive regulation of blood coagulation and biological process this GO :0030195 and negative regulation of blood coagulation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030336 and negative regulation of cell migration and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0033629 and negative regulation of cell adhesion mediated by integrin and biological process this GO :0035491 and positive regulation of leukotriene production involved in inflammatory response and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042730 and fibrinolysis and biological process this GO :0045087 and innate immune response and biological process this GO :0045765 and regulation of angiogenesis and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048260 and positive regulation of receptor-mediated endocytosis and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050829 and defense response to Gram-negative bacterium and biological process this GO :0051918 and negative regulation of fibrinolysis and biological process this GO :0061044 and negative regulation of vascular wound healing and biological process this GO :0061045 and negative regulation of wound healing and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0090026 and positive regulation of monocyte chemotaxis and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2000098 and negative regulation of smooth muscle cell-matrix adhesion and biological process this GO :2000352 and negative regulation of endothelial cell apoptotic process and biological process, Extracellular, PAI and PAI-1 and PAI1 and PLANH1, SERPINE1 and IDBG-32959 and ENSG00000106366 and 5054, SERPINE1 and IDBG-640415 and ENSBTAG00000014465 and 281375, Serpine1 and IDBG-204786 and ENSMUSG00000037411 and 18787, clade E (nexin, member 1, plasminogen activator inhibitor type 1), protein binding, this GO :0001300 and chronological cell aging and biological process this GO :0001525 and angiogenesis and biological process this GO :0002020 and protease binding and molecular function this GO :0002576 and platelet degranulation and biological process this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0004867 : serine-type endopeptidase inhibitor activity and also this GO :0005102 : receptor binding and also this GO :0005515 : protein binding, this GO :0004867 : serine-type endopeptidase inhibitor activity, this GO :0005102 : receptor binding, this GO :0005515 : protein binding, serpin peptidase inhibitor |
| Identity: |
8583 |
| Long gene name: |
serpin family E member 1 |
| Synonyms gene: |
PLANH1 PAI1 |
| Synonyms gene name: |
clade E (nexin, clade E (nexin, member 1 , member 1 serpin peptidase inhibitor, plasminogen activator inhibitor type 1), plasminogen activator inhibitor type 1), serine (or cysteine) proteinase inhibitor |
| Synonyms: |
PAI |
| Synonyms name: |
plasminogen activator inhibitor, type I |
| Locus: |
7q22, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M16006 |
| Entrez gene record: |
5054 |
| Pubmed identfication: |
3097076 2891140 24172014 |
| RefSeq identity: |
NM_000602 |
| Classification: |
Serpin peptidase inhibitors |
| Havana BLAST/BLAT: |
OTTHUMG00000157107 |
| Locus Specific Databases: |
LRG_597 |