| Long name: |
232) Monoclonal Antibody, 86, 123, 269, APEX1 (1518CT337 |
| Also known as: |
232) Monoclonal Antibody, 86, 123, 269, APEX1 (1518CT337 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
APEX1 |
| Specificity: |
This is a highly specific antibody against APEX1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
1518CT337, 86, 123, 232, 269 |
| Source: |
This APEX1 antibody is generated from a mouse immunized with a recombinant protein of human APEX1 |
| Gene ID number: |
328 |
| Swiss Prot: |
P27695 |
| Tested Applications: |
IF, IHC, WB |
| Recommended dilutions: |
IF(1:25), IHC(1:25), 25) , WB(0 |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites, Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site, Jul 2008], Splice variants have been found for this gene, This gene encodes the major AP endonuclease in human cells, [provided by RefSeq, all encode the same protein, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases, Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AP endonuclease 1, APE-1, APE1, APEN, APEX, APEX nuclease, APEX1, APX, Apurinic-apyrimidinic endonuclease 1, DNA-(apurinic or apyrimidinic site) lyase, HAP1, REF-1, REF1, Redox factor-1, APE |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
232) Monoclonal, 86, 123, 269, APEX1 (1518CT337 |
| Short name: |
232) Monoclonal Antibody, 86, 123, 269, APEX1 (1518CT337 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
232) monoclonal (Antibody to), 86, 123, 269, APEX1 (1518CT337 |
| Alternative technique: |
antibodies |
| Identity: |
587 |
| Gene: |
APEX1 |
More about : APEX1 |
| Long gene name: |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
| Synonyms gene: |
APEX |
| Synonyms gene name: |
APEX nuclease (multifunctional DNA repair enzyme) APEX nuclease (multifunctional DNA repair enzyme) 1 |
| Synonyms: |
APE REF1 HAP1 APX APEN REF-1 APE-1 |
| Locus: |
14q11, 2 |
| Discovery year: |
1997-05-22 |
| GenBank acession: |
X59764 |
| Entrez gene record: |
328 |
| RefSeq identity: |
NM_001641 |
| Havana BLAST/BLAT: |
OTTHUMG00000029544 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |