| known also as: |
Anti-Rabbit Polyclonal (IgG) to Human VHL / Von Hippel Lindau |
| known also as: |
Rabbit PAb (IgG) to Human VHL / Von Hippel Lindau |
| known also as: |
Lapin Polyclonal (IgG) to Homo sapiens VHL / Von Hippel Lindau |
| known also as: |
VHL / Von Hippel Lindau |
| known also as: |
Elongin binding protein, HRCA1, Human VHL, PVHL, Protein G7, RCA1, VHL, VHL1, Von Hippel Lindau, Von Hippel-Lindau syndrome, Anti-VHL / Von Hippel Lindau Antibody (aa34-83) IHC-plus |
| Other names: |
E3 ubiquitin protein ligase, Protein G7, Von Hippel-Lindau disease tumor suppressor, elongin binding protein, pVHL, protein G7, von Hippel-Lindau disease tumor suppressor, von Hippel-Lindau tumor suppressor, von Hippel-Lindau disease tumor suppressor isoform 1 |
| Gene name: |
VHL |
| Other gene names: |
HRCA1, N/A, RCA1, VHL, VHL1, pVHL, VHL |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Mouse, Rat, Human |
| Specificity and cross-reactivity: |
VHL (Ab-68) Antibody detects endogenous levels of total VHL protein |
| Purification method: |
Immunoaffinity Purified |
| Form/Appearance: |
0, 150 mM sodium chloride, 50% glycerol, Ca2+), pH 7, 02% sodium azide, 4, PBS (without Mg2+ |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
for up to one year, Store productone should be stored at -20 degrees Celsius |
| Tested for:: |
ELISA (EIA), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| About: |
2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum  |
| Gene target: |
PAb VHL / Von Hippel Lindau |
| Short name: |
PAb (IgG) VHL / Von Hippel Lindau |
| Technique: |
IgGs, IgG |
| Isotype: |
IgG |
| Species: |
Humans, Human |
| Alternative name: |
E3 ubiquitin protein ligase / Von Hippel Lindau, sapiens von Hippel-Lindau tumor suppressor, polyclonal (Immunoglobulin G) to H |
| Alternative technique: |
immunoglobulins |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0006508 and proteolysis and biological process this GO :0006950 and response to stress and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0019899 and enzyme binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045111 and intermediate filament cytoskeleton and cellular component this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0050821 and protein stabilization and biological process this GO :0061418 and regulation of transcription from RNA polymerase II promoter in response to hypoxia and biological process this GO :0061428 and negative regulation of transcription from RNA polymerase II promoter in response to hypoxia and biological process this GO :0071456 and cellular response to hypoxia and biological process, E3 ubiquitin protein ligase, HRCA1 and pVHL and RCA1 and VHL1, VHL and IDBG-17819 and ENSG00000134086 and 7428, Vhl and IDBG-178105 and ENSMUSG00000033933 and 22346, enzyme binding, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000902 and cell morphogenesis and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005829 and cytosol and cellular component this GO :0006355 and regulation of transcription, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0019899 : enzyme binding, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0019899 : enzyme binding, 79817 and IDBG-644624 and ENSBTAG00000016101 and 540957, von Hippel-Lindau tumor suppressor |
| Identity: |
12687 |
| Gene: |
VHL |
More about : VHL |
| Long gene name: |
von Hippel-Lindau tumor suppressor |
| Synonyms gene name: |
E3 ubiquitin protein ligase , von Hippel-Lindau syndrome von Hippel-Lindau tumor suppressor |
| Synonyms: |
VHL1 |
| Locus: |
3p25, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
L15409 |
| Entrez gene record: |
7428 |
| Pubmed identfication: |
9671762 |
| RefSeq identity: |
NM_000551 |
| Havana BLAST/BLAT: |
OTTHUMG00000128668 |
| Locus Specific Databases: |
UMD Locus Specific Databases LRG_322 |