| Long name: |
25) Monoclonal Antibody, 89, ULK3 (1404CT148 |
| Also known as: |
25) Monoclonal Antibody, 89, ULK3 (1404CT148 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ULK3 |
| Specificity: |
This is a highly specific antibody against ULK3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
1404CT148, 25, 89 |
| Source: |
This ULK3 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 435-468 amino acids from the C-terminal region of human ULK3 |
| Gene ID number: |
25989 |
| Swiss Prot: |
Q6PHR2 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB( 1:1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, Also acts as a regulator of autophagy: following cellular senescence, GLI2 and/or GLI3), Phosphorylates in vitro GLI2, Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, able to induce autophagy, activating it and promoting its nuclear translocation, although less efficiently, as well as GLI1 and GLI3, autophosphorylates and mediates phosphorylation of GLI2, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy |
| Purification method: |
This antibody is purified through a protein G column, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ULK3, Unc-51-like kinase 3, Serine/threonine-protein kinase ULK3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
25) Monoclonal, 89, ULK3 (1404CT148 |
| Short name: |
25) Monoclonal Antibody, 89, ULK3 (1404CT148 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
25) monoclonal (Antibody to), 89, ULK3 (1404CT148 |
| Alternative technique: |
antibodies |
| Identity: |
19703 |
| Gene: |
ULK3 |
More about : ULK3 |
| Long gene name: |
unc-51 like kinase 3 |
| Synonyms gene name: |
elegans) , unc-51-like kinase 3 (C |
| Synonyms: |
DKFZP434C131 FLJ90566 |
| Locus: |
15q24, 1 |
| Discovery year: |
2005-01-19 |
| GenBank acession: |
BC048289 |
| Entrez gene record: |
25989 |
| RefSeq identity: |
NM_015518 |
| Havana BLAST/BLAT: |
OTTHUMG00000173020 |