| Long name: |
140) Monoclonal Antibody, 170, USP5 (1340CT704 |
| Also known as: |
140) Monoclonal Antibody, 170, USP5 (1340CT704 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
USP5 |
| Specificity: |
This is a highly specific antibody against USP5 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
1340CT704, 140, 170 |
| Source: |
This USP5 antibody is generated from a mouse immunized with a recombination protein from the human region of human USP5 |
| Gene ID number: |
8078 |
| Swiss Prot: |
P45974 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB(1:1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity, Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly, Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition, Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers |
| Purification method: |
This antibody is purified through a protein G column, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Deubiquitinating enzyme 5, Isopeptidase T, USP5, Ubiquitin carboxyl-terminal hydrolase 5, Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5, ISOT |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
140) Monoclonal, 170, USP5 (1340CT704 |
| Short name: |
140) Monoclonal Antibody, 170, USP5 (1340CT704 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
140) monoclonal (Antibody to), 170, USP5 (1340CT704 |
| Alternative technique: |
antibodies |
| Identity: |
12628 |
| Gene: |
USP5 |
More about : USP5 |
| Long gene name: |
ubiquitin specific peptidase 5 |
| Synonyms gene name: |
ubiquitin specific peptidase 5 (isopeptidase T) |
| Synonyms: |
IsoT |
| Synonyms name: |
isopeptidase T |
| Locus: |
12p13 |
| Discovery year: |
1999-02-01 |
| GenBank acession: |
U35116 |
| Pubmed identfication: |
12838346 8723724 |
| Classification: |
Ubiquitin specific peptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000169233 |