| Long name: |
189) Monoclonal Antibody, 193, USP11 (1220CT620 |
| Also known as: |
189) Monoclonal Antibody, 193, USP11 (1220CT620 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
USP11 |
| Specificity: |
This is a highly specific antibody against USP11 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
1220CT620, 189, 193 |
| Source: |
This USP11 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 32-300 amino acids from the N-terminal region of human USP11 |
| Gene ID number: |
8237 |
| Swiss Prot: |
P51784 |
| Tested Applications: |
FCM, WB |
| Recommended dilutions: |
FC(1:25), WB(1:1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
'Lys-29' and 'Lys-48'-linked ubiquitin chains (in vitro) (PubMed:24724799), Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains, Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, Inhibits the degradation of target proteins by the proteasome (PubMed:12084015), Plays a role in the regulation of DNA repair after double-stranded DNA breaks (PubMed:15314155, Plays a role in the regulation of pathways leading to NF-kappa-B activation (PubMed:17897950, PubMed:15314155, PubMed:17897950, PubMed:19874889, PubMed:19874889), PubMed:20233726, PubMed:20233726), PubMed:24724799), and extremely low activity with 'Lys-27', Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains (PubMed:12084015 |
| Purification method: |
This antibody is purified through a protein G column, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Deubiquitinating enzyme 11, USP11, Ubiquitin carboxyl-terminal hydrolase 11, Ubiquitin thioesterase 11, Ubiquitin-specific-processing protease 11, UHX1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
189) Monoclonal, 193, USP11 (1220CT620 |
| Short name: |
189) Monoclonal Antibody, 193, USP11 (1220CT620 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
189) monoclonal (Antibody to), 193, USP11 (1220CT620 |
| Alternative technique: |
antibodies |
| Identity: |
12609 |
| Gene: |
USP11 |
More about : USP11 |
| Long gene name: |
ubiquitin specific peptidase 11 |
| Synonyms gene name: |
ubiquitin specific protease 11 |
| Synonyms: |
UHX1 |
| Locus: |
Xp11, 3 |
| Discovery year: |
1999-02-01 |
| GenBank acession: |
U44839 |
| Entrez gene record: |
8237 |
| Pubmed identfication: |
12838346 |
| RefSeq identity: |
NM_004651 |
| Classification: |
Ubiquitin specific peptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000021437 |
| Locus Specific Databases: |
Mental Retardation database |