| known also as: |
Anti-Rabbit Polyclonal (IgG) to Human IRS1 / IRS-1 |
| known also as: |
Rabbit PAb (IgG) to Human IRS1 / IRS-1 |
| known also as: |
Lapin Polyclonal (IgG) to Homo sapiens IRS1 / IRS-1 |
| known also as: |
IRS1 / IRS-1 |
| known also as: |
HIRS-1, Human IRS1, IRS-1, IRS-1, IRS1, Insulin receptor substrate 1, Anti-IRS1 / IRS-1 Antibody (aa289-338) IHC-plus |
| Other names: |
IRS-1, Insulin receptor substrate 1, N/A, insulin receptor substrate 1, insulin receptor substrate 1, insulin receptor substrate 1 |
| Gene name: |
IRS1 |
| Gene name synonims: |
IRS-1 |
| Other gene names: |
HIRS-1, IRS-1, IRS1, IRS1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Mouse, Rat, Human |
| Specificity and cross-reactivity: |
IRS1 Antibody detects endogenous levels of total IRS1 protein |
| Purification method: |
Immunoaffinity Purified |
| Form/Appearance: |
0, 150 mM sodium chloride, 50% glycerol, Ca2+), pH 7, 02% sodium azide, 4, PBS (without Mg2+ |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
avoid freeze thaw cycles, long term aliquot and store productone should be stored at -20 degrees Celsius, Short term Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| About: |
2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Gene target: |
PAb IRS1 / IRS-1 |
| Short name: |
PAb (IgG) IRS1 / IRS-1 |
| Technique: |
IgGs, IgG |
| Isotype: |
IgG |
| Species: |
Humans, Human |
| Alternative name: |
sapiens insulin receptor substrate 1 / IRS-1, polyclonal (Immunoglobulin G) to H |
| Alternative technique: |
immunoglobulins |
| Alternative to gene target: |
HIRS-1, IRS1 and IDBG-647770 and ENSBTAG00000021308 and 538598, IRS1 and IDBG-82407 and ENSG00000169047 and 3667, Irs1 and IDBG-173589 and ENSMUSG00000055980 and 16367, nuclei, phosphatidylinositol 3-kinase binding, this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0005068 and transmembrane receptor protein tyrosine kinase adaptor activity and molecular function this GO :0005080 and protein kinase C binding and molecular function this GO :0005158 and insulin receptor binding and molecular function this GO :0005159 and insulin-like growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005899 and insulin receptor complex and cellular component this GO :0005901 and caveola and cellular component this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0010907 and positive regulation of glucose metabolic process and biological process this GO :0014065 and phosphatidylinositol 3-kinase signaling and biological process this GO :0016042 and lipid catabolic process and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030335 and positive regulation of cell migration and biological process this GO :0030879 and mammary gland development and biological process this GO :0032000 and positive regulation of fatty acid beta-oxidation and biological process this GO :0032868 and response to insulin and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0034504 and protein localization to nucleus and biological process this GO :0036064 and ciliary basal body and cellular component this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0042593 and glucose homeostasis and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043434 and response to peptide hormone and biological process this GO :0043491 and protein kinase B signaling and biological process this GO :0043548 and phosphatidylinositol 3-kinase binding and molecular function this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045725 and positive regulation of glycogen biosynthetic process and biological process this GO :0046326 and positive regulation of glucose import and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0046628 and positive regulation of insulin receptor signaling pathway and biological process this GO :0046676 and negative regulation of insulin secretion and biological process this GO :0048009 and insulin-like growth factor receptor signaling pathway and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :2001275 and positive regulation of glucose import in response to insulin stimulus and biological process, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0005068 : transmembrane receptor protein tyrosine kinase adaptor activity and also this GO :0005080 : protein kinase C binding and also this GO :0005158 : insulin receptor binding and also this GO :0005159 : insulin-like growth factor receptor binding and also this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding and also this GO :0042169 : SH2 domain binding and also this GO :0043548 : phosphatidylinositol 3-kinase binding, this GO :0005068 : transmembrane receptor protein tyrosine kinase adaptor activity, this GO :0005080 : protein kinase C binding, this GO :0005158 : insulin receptor binding, this GO :0005159 : insulin-like growth factor receptor binding, this GO :0005515 : protein binding, this GO :0019901 : protein kinase binding, this GO :0042169 : SH2 domain binding, this GO :0043548 : phosphatidylinositol 3-kinase binding, insulin receptor substrate 1 |
| Identity: |
6125 |
| Gene: |
IRS1 |
More about : IRS1 |
| Long gene name: |
insulin receptor substrate 1 |
| Synonyms: |
HIRS-1 |
| Locus: |
2q36, 3 |
| Discovery year: |
1992-08-24 |
| Entrez gene record: |
3667 |
| Pubmed identfication: |
1648180 |
| RefSeq identity: |
NM_005544 |
| Classification: |
Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000133179 |