| Long name: |
128, 36) Monoclonal Antibody, RNF20 (1594CT552 |
| Also known as: |
128, 36) Monoclonal Antibody, RNF20 (1594CT552 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RNF20 |
| Specificity: |
This is a highly specific antibody against RNF20 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
36, 128, 1594CT552 |
| Source: |
This RNF20 antibody is generated from a mouse immunized with a recombinant protein of human RNF20 |
| Gene ID number: |
56254 |
| Swiss Prot: |
Q5VTR2 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB(1:2000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, It thereby plays a central role inb histone code and gene regulation, Mediates the polyubiquitination of isoform 2 of PA2G4 in cancer cells leading to its proteasome-mediated degradation, Recruited to the MDM2 promoter, Required for transcriptional activation of Hox genes, The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, and thereby acts as a transcriptional coactivator, probably by being recruited by p53/TP53, reports about the cooperation with UBE2E1/UBCH are contradictory, respectively), Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1) |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
BRE1-A, BRE1A, E3 ubiquitin-protein ligase BRE1A, RING finger protein 20, RNF20, hBRE1, BRE1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
128, 36) Monoclonal, RNF20 (1594CT552 |
| Short name: |
128, 36) Monoclonal Antibody, RNF20 (1594CT552 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
128, 36) monoclonal (Antibody to), RNF20 (1594CT552 |
| Alternative technique: |
antibodies |
| Identity: |
10062 |
| Gene: |
RNF20 |
More about : RNF20 |
| Long gene name: |
ring finger protein 20 |
| Synonyms gene name: |
E3 ubiquitin protein ligase , ring finger protein 20 ring finger protein 20 |
| Synonyms: |
FLJ20382 FLJ11189 KAIA2779 BRE1A hBRE1 BRE1 |
| Synonyms name: |
BRE1 E3 ubiquitin ligase homolog (S, cerevisiae) |
| Locus: |
9q31, 1 |
| Discovery year: |
2000-05-23 |
| GenBank acession: |
AF265230 |
| Entrez gene record: |
56254 |
| Pubmed identfication: |
16337599 12876294 18832071 19037095 |
| RefSeq identity: |
NM_019592 |
| Classification: |
Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000020385 |