| known also as: |
Anti-Rabbit Polyclonal (IgG) to Human EDA2R / XEDAR |
| known also as: |
Rabbit PAb (IgG) to Human EDA2R / XEDAR |
| known also as: |
Lapin Polyclonal (IgG) to Homo sapiens EDA2R / XEDAR |
| known also as: |
EDA2R / XEDAR |
| known also as: |
EDA-A2 receptor, EDA-A2R, EDA2R, EDAA2R, EDAR2, Ectodysplasin A2 receptor, Human EDA2R, TNFRSF27, XEDAR, XEDAR, Anti-EDA2R / XEDAR Antibody IHC-plus |
| Other names: |
EDA-A2 receptor, EDA-A2 receptor, Tumor necrosis factor receptor superfamily member 27, X-linked ectodysplasin-A2 receptor, X-linked ectodysplasin-A2 receptor, ectodysplasin A2 receptor, tumor necrosis factor receptor superfamily member 27, tumor necrosis factor receptor superfamily member XEDAR, tumor necrosis factor receptor superfamily member 27 isoform 1 |
| Gene name: |
EDA2R |
| Gene name synonims: |
XEDAR |
| Other gene names: |
EDA-A2 receptor, EDA-A2R, EDA2R, EDAA2R, TNFRSF27, TNFRSF27, XEDAR, XEDAR, EDA2R |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Binding of ectodysplasin to XEDAR results in the induction of apoptosis, New evidence suggests XEDAR may also be involved in skeletal muscle development, Two predominant isoforms of XEDAR exist, XEDAR is a homologue of the ectodermal dysplasia receptor (EDAR), XEDAR-s and XEDAR-L, a 33kD type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and binds to an isoform of ectodysplasin termed EDA-A2, and is thought to be involved ectodermal organ development, produced by alternative splicing, Detects human X-linked ectodermal dysplasia receptor (XEDAR) |
| Purification method: |
Purified |
| Form/Appearance: |
0, 02% sodium azide, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
avoid freeze thaw cycles, long term aliquot and store productone should be stored at -20 degrees Celsius, Short term Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°, humans , ssp |
| About: |
2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Gene target: |
PAb EDA2R / XEDAR |
| Short name: |
PAb (IgG) EDA2R / XEDAR Antibody |
| Technique: |
IgGs, antibodies against human proteins, antibodies for, Antibody |
| Isotype: |
IgG |
| Species: |
Humans, Human |
| Alternative name: |
sapiens ectodysplasin A2 receptor / XEDAR (Antibody to), polyclonal (Immunoglobulin G) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
EDA2R and IDBG-636425 and ENSBTAG00000047326 and 100301324, EDA2R and IDBG-73673 and ENSG00000131080 and 60401, Eda2r and IDBG-161374 and ENSMUSG00000034457 and 245527, Plasma membranes, protein binding, this GO :0004872 and receptor activity and molecular function this GO :0005031 and tumor necrosis factor-activated receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0008544 and epidermis development and biological process this GO :0009790 and embryo development and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0030154 and cell differentiation and biological process this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0072332 and intrinsic apoptotic signaling pathway by p53 class mediator and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005031 : tumor necrosis factor-activated receptor activity and also this GO :0005515 : protein binding, this GO :0005031 : tumor necrosis factor-activated receptor activity, this GO :0005515 : protein binding, ectodysplasin A2 receptor |
| Identity: |
17756 |
| Gene: |
EDA2R |
More about : EDA2R |
| Long gene name: |
ectodysplasin A2 receptor |
| Synonyms: |
XEDAR EDA-A2R EDAA2R TNFRSF27 |
| Locus: |
Xq12 |
| Discovery year: |
2004-08-17 |
| GenBank acession: |
AF298812 |
| Entrez gene record: |
60401 |
| Pubmed identfication: |
11039935 |
| RefSeq identity: |
NM_021783 |
| Classification: |
Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000021736 |
| Locus Specific Databases: |
Mental Retardation database |