| Long name: |
4) Monoclonal Antibody, 6, EPHA5 (46CT61 |
| Also known as: |
4) Monoclonal Antibody, 6, EPHA5 (46CT61 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
EPHA5 |
| Specificity: |
This is a highly specific antibody against EPHA5 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
4, 46CT61, 6 |
| Source: |
Purified His-tagged EPHA5 protein(Fragment) was used to produced this monoclonal antibody |
| Gene ID number: |
2044 |
| Swiss Prot: |
P54756 |
| Tested Applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:10~50), WB(1:1000-2000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5, Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, In addition to its function in the nervous system, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis, entorhino-hippocampal and hippocamposeptal pathways, leading to contact-dependent bidirectional signaling into neighboring cells, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity), Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells |
| Purification method: |
This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
BSK, Brain-specific kinase, CEK7, EHK-1, EHK1, EPH homology kinase 1, EPH-like kinase 7, EPHA5, Ephrin type-A receptor 5, HEK7, TYRO4, EK7 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
4) Monoclonal, 6, EPHA5 (46CT61 |
| Short name: |
4) Monoclonal Antibody, 6, EPHA5 (46CT61 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
4) monoclonal (Antibody to), 6, EPHA5 (46CT61 |
| Alternative technique: |
antibodies |
| Identity: |
3389 |
| Gene: |
EPHA5 |
More about : EPHA5 |
| Long gene name: |
EPH receptor A5 |
| Synonyms gene name: |
EphA5 |
| Synonyms: |
Hek7 TYRO4 CEK7 EHK1 |
| Locus: |
4q13, 1-q13, 2 |
| Discovery year: |
1997-10-10 |
| GenBank acession: |
L36644 |
| Entrez gene record: |
2044 |
| Pubmed identfication: |
9267020 7528718 |
| RefSeq identity: |
NM_004439 |
| Classification: |
Sterile alpha motif domain containing Fibronectin type III domain containing EPH receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000129273 |