| Long name: |
4) Monoclonal Antibody, 5, DRD4 (625CT1 |
| Also known as: |
4) Monoclonal Antibody, 5, DRD4 (625CT1 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DRD4 |
| Specificity: |
This is a highly specific antibody against DRD4 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
4, 5, 625CT1 |
| Source: |
This DRD4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 365-391 amino acids from the Central region of human DRD4 |
| Gene ID number: |
1815 |
| Swiss Prot: |
P21917 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB(1:1000-5000) |
| Cross reactivity: |
Mouse, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Its activity is mediated by G proteins which inhibit adenylyl cyclase, Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells (By similarity), an area of the brain that regulates emotion and complex behavior, Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain |
| Purification method: |
09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0 |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
D(2C) dopamine receptor, D(4) dopamine receptor, DRD4, Dopamine D4 receptor, D4DR |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
4) Monoclonal, 5, DRD4 (625CT1 |
| Short name: |
4) Monoclonal Antibody, 5, DRD4 (625CT1 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
4) monoclonal (Antibody to), 5, dopamine receptor D4 (625CT1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
D4DR, DRD4 and IDBG-17519 and ENSG00000069696 and 1815, Drd4 and IDBG-212125 and ENSMUSG00000025496 and 13491, Plasma membranes, coupled via Gi/ this GO , coupled via Gi/ this GO and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004952 : dopamine receptor activity and also this GO :0005515 : protein binding and also this GO :0008144 : drug binding and also this GO :0015459 : potassium channel regulator activity and also this GO :0017124 : SH3 domain binding and also this GO :0035240 : dopamine binding and also this GO :0042802 : identical protein binding, coupled via Gi/ this GO and molecular function this GO :0001662 and behavioral fear response and biological process this GO :0001963 and synaptic transmission, dopamine neurotransmitter receptor activity, dopaminergic and biological process this GO :0001975 and response to amphetamine and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004952 and dopamine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005938 and cell cortex and cellular component this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007194 and negative regulation of adenylate cyclase activity and biological process this GO :0007195 and adenylate cyclase-inhibiting dopamine receptor signaling pathway and biological process this GO :0007212 and dopamine receptor signaling pathway and biological process this GO :0007614 and short-term memory and biological process this GO :0007623 and circadian rhythm and biological process this GO :0008144 and drug binding and molecular function this GO :0008306 and associative learning and biological process this GO :0008344 and adult locomotory behavior and biological process this GO :0008355 and olfactory learning and biological process this GO :0009648 and photoperiodism and biological process this GO :0012506 and vesicle membrane and cellular component this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0017124 and SH3 domain binding and molecular function this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0030818 and negative regulation of cAMP biosynthetic process and biological process this GO :0032417 and positive regulation of sodium:proton antiporter activity and biological process this GO :0033674 and positive regulation of kinase activity and biological process this GO :0034776 and response to histamine and biological process this GO :0035176 and social behavior and biological process this GO :0035240 and dopamine binding and molecular function this GO :0042053 and regulation of dopamine metabolic process and biological process this GO :0042417 and dopamine metabolic process and biological process this GO :0042596 and fear response and biological process this GO :0042752 and regulation of circadian rhythm and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043025 and neuronal cell body and cellular component this GO :0043195 and terminal bouton and cellular component this GO :0043197 and dendritic spine and cellular component this GO :0043679 and axon terminus and cellular component this GO :0046928 and regulation of neurotransmitter secretion and biological process this GO :0048148 and behavioral response to cocaine and biological process this GO :0048149 and behavioral response to ethanol and biological process this GO :0048545 and response to steroid hormone and biological process this GO :0050482 and arachidonic acid secretion and biological process this GO :0050709 and negative regulation of protein secretion and biological process this GO :0050804 and regulation of synaptic transmission and biological process this GO :0050848 and regulation of calcium-mediated signaling and biological process this GO :0051586 and positive regulation of dopamine uptake involved in synaptic transmission and biological process this GO :0060041 and retina development in camera-type eye and biological process this GO :0060080 and regulation of inhibitory postsynaptic membrane potential and biological process this GO :0060406 and positive regulation of penile erection and biological process this GO :1901386 and negative regulation of voltage-gated calcium channel activity and biological process this GO :2000463 and positive regulation of excitatory postsynaptic membrane potential and biological process, this GO :0000187 and activation of MAPK activity and biological process this GO :0001591 and dopamine neurotransmitter receptor activity, this GO :0001591 : dopamine neurotransmitter receptor activity, this GO :0001591 : dopamine neurotransmitter receptor activity, this GO :0004930 : G-protein coupled receptor activity, this GO :0004952 : dopamine receptor activity, this GO :0005515 : protein binding, this GO :0008144 : drug binding, this GO :0015459 : potassium channel regulator activity, this GO :0017124 : SH3 domain binding, this GO :0035240 : dopamine binding, this GO :0042802 : identical protein binding, dopamine receptor D4 |
| Identity: |
3025 |
| Gene: |
DRD4 |
More about : DRD4 |
| Long gene name: |
dopamine receptor D4 |
| Locus: |
11p15, 5 |
| Discovery year: |
1991-07-16 |
| GenBank acession: |
L12398 |
| Entrez gene record: |
1815 |
| RefSeq identity: |
NM_000797 |
| Classification: |
Dopamine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133312 |