| Long name: |
1, 1) Monoclonal Antibody, ANPEP (496CT9 |
| Also known as: |
1, 1) Monoclonal Antibody, ANPEP (496CT9 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ANPEP |
| Specificity: |
This is a highly specific antibody against ANPEP |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
1, 1, 496CT9 |
| Source: |
Purified His-tagged ANPEP protein(Fragment) was used to produced this monoclonal antibody |
| Gene ID number: |
290 |
| Swiss Prot: |
P15144 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB(1:100~500) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
(Microbial infection) Acts as a receptor for human coronavirus 229E/HCoV-229E, Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions, In case of human coronavirus 229E (HCoV-229E) infection, Is also implicated as a regulator of IL-8 bioavailability in the endometrium, Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion, May be involved in the metabolism of regulatory peptides of diverse cell types, May play a critical role in the pathogenesis of cholesterol gallstone disease, Mediates as well human cytomegalovirus (HCMV) infection, Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases, and chemokines, and therefore may contribute to the regulation of angiogenesis, neuropeptides, responsible for the processing of peptide hormones, serves as receptor for HCoV-229E spike glycoprotein, such as angiotensin III and IV, Broad specificity aminopeptidase |
| Purification method: |
This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ANPEP, AP-M, AP-N, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, CD13, GP150, LAP1, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, P150, PEPN, hAPN, APN |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
1, 1) Monoclonal, ANPEP (496CT9 |
| Short name: |
1, 1) Monoclonal Antibody, ANPEP (496CT9 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
1, 1) monoclonal (Antibody to), ANPEP (496CT9 |
| Alternative technique: |
antibodies |
| Identity: |
500 |
| Gene: |
ANPEP |
More about : ANPEP |
| Long gene name: |
alanyl aminopeptidase, membrane |
| Synonyms gene: |
CD13 PEPN |
| Synonyms gene name: |
alanyl (membrane) aminopeptidase |
| Synonyms: |
LAP1 gp150 p150 |
| Synonyms name: |
aminopeptidase N aminopeptidase M microsomal aminopeptidase membrane alanyl aminopeptidase |
| Locus: |
15q26, 1 |
| Discovery year: |
1989-02-28 |
| GenBank acession: |
M22324 |
| Entrez gene record: |
290 |
| Pubmed identfication: |
2428842 1977688 |
| Classification: |
CD molecules Aminopeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000149814 |