| Long name: |
2, 4) Monoclonal Antibody, 6, ITGAX/CD11c (428CT12 |
| Also known as: |
2, 4) Monoclonal Antibody, 6, ITGAX/CD11c (428CT12 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ITGAX/CD11c |
| Specificity: |
This is a highly specific antibody against ITGAX/CD11c |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
2, 4, 428CT12, 6 |
| Source: |
This ITGAX/CD11c antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human ITGAX/CD11c |
| Gene ID number: |
3687 |
| Swiss Prot: |
P20702 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB(1:100~500) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
It is especially important in monocyte adhesion and chemotaxis, It mediates cell-cell interaction during inflammatory responses, It recognizes the sequence G-P-R in fibrinogen, Integrin alpha-X/beta-2 is a receptor for fibrinogen |
| Purification method: |
This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CD11 antigen-like family member C, ITGAX, Integrin alpha-X, Leu M5, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion receptor p150, SLEB6, 95, 95 alpha chain, CD11C |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
2, 4) Monoclonal, 6, ITGAX/CD11c (428CT12 |
| Short name: |
2, 4) Monoclonal Antibody, 6, ITGAX/CD11c (428CT12 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
a X (complement component 3 receptor 4 subunit)/CD11c (428CT12, 2, 4) monoclonal (Antibody to), 6, integrin |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD11C and SLEB6, Cell surfaces, ITGAX and IDBG-28212 and ENSG00000140678 and 3687, Itgax and IDBG-210550 and ENSMUSG00000030789 and 16411, alpha X (complement component 3 receptor 4 subunit), metal ion binding, this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0008305 and integrin complex and cellular component this GO :0009887 and organ morphogenesis and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0030198 and extracellular matrix organization and biological process this GO :0045087 and innate immune response and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050900 and leukocyte migration and biological process this GO :0051607 and defense response to virus and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005515 : protein binding and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0046872 : metal ion binding, integrin |
| Identity: |
6152 |
| Gene: |
ITGAX |
More about : ITGAX |
| Long gene name: |
integrin subunit alpha X |
| Synonyms gene: |
CD11C |
| Synonyms gene name: |
alpha X (antigen CD11C (p150), alpha X (complement component 3 receptor 4 subunit) , alpha polypeptide) integrin, integrin |
| Synonyms: |
CD11c |
| Synonyms name: |
complement component 3 receptor 4 subunit |
| Locus: |
16p11, 2 |
| Discovery year: |
1988-08-15 |
| GenBank acession: |
BC038237 |
| Entrez gene record: |
3687 |
| Pubmed identfication: |
3284962 2303426 |
| RefSeq identity: |
NM_000887 |
| Classification: |
Complement system Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000132465 |