| Long name: |
2, 2) Monoclonal Antibody, ATG4C (287CT12 |
| Also known as: |
2, 2) Monoclonal Antibody, ATG4C (287CT12 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ATG4C |
| Specificity: |
This is a highly specific antibody against ATG4C |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
2, 2, 287CT12 |
| Source: |
This ATG4C monoclonal antibody is generated from mouse immunized with ATG4C recombinant protein |
| Gene ID number: |
84938 |
| Swiss Prot: |
Q96DT6 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB(1:100) |
| Cross reactivity: |
Mouse |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, Has also an activity of delipidating enzyme for the PE-conjugated forms, Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity), to reveal a C-terminal glycine, which is necessary for autophagy, Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy |
| Purification method: |
This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
APG4-C, ATG4C, AUT-like 3 cysteine endopeptidase, AUTL1, AUTL3, Autophagin-3, Autophagy-related cysteine endopeptidase 3, Autophagy-related protein 4 homolog C, Cysteine protease ATG4C, APG4C |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
2, 2) Monoclonal, ATG4C (287CT12 |
| Short name: |
2, 2) Monoclonal Antibody, ATG4C (287CT12 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
2, 2) monoclonal (Antibody to), ATG4C (287CT12 |
| Alternative technique: |
antibodies |
| Identity: |
16040 |
| Gene: |
ATG4C |
More about : ATG4C |
| Long gene name: |
autophagy related 4C cysteine peptidase |
| Synonyms gene: |
AUTL1 APG4C |
| Synonyms gene name: |
AUT (S, AUT-like 1, cerevisiae) APG4 autophagy 4 homolog C (S, cerevisiae) ATG4 autophagy related 4 homolog C (S, cerevisiae) autophagy related 4C, cerevisiae)-like 1, cysteine endopeptidase, cysteine endopeptidase (S, cysteine peptidase |
| Synonyms: |
FLJ14867 AUTL3 |
| Locus: |
1p31, 3 |
| Discovery year: |
2001-07-13 |
| GenBank acession: |
AK027773 |
| Entrez gene record: |
84938 |
| Pubmed identfication: |
12446702 |
| RefSeq identity: |
NM_032852 |
| Classification: |
Autophagy related |
| Havana BLAST/BLAT: |
OTTHUMG00000009142 |