| Long name: |
ILK (AF22F1) Monoclonal Antibody |
| Also known as: |
ILK (AF22F1) Monoclonal Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ILK |
| Specificity: |
This is a highly specific antibody against ILK |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
AF22F1 |
| Concentration: |
1ug per 1ul |
| Source: |
Recombinant human protein purified from E, coli (His-ILK) |
| Gene ID number: |
3611 |
| Swiss Prot: |
Q13418 |
| Tested Applications: |
WB |
| Recommended dilutions: |
0 ug/mL), WB (1 |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Could be implicated in mediating cell architecture, Focal adhesion protein part of the complex ILK-PINCH, May act as a mediator of inside-out integrin signaling, Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells, but also AKT1 and GSK3B, Receptor-proximal protein kinase regulating integrin-mediated signal transduction |
| Purification method: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
59 kDa serine/threonine-protein kinase, HEL-S-28, ILK, ILK-1, ILK-2, ILK1, ILK2, Integrin-linked protein kinase, p59ILK, P59 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
ILK (AF22F1) Monoclonal |
| Short name: |
ILK (AF22F1) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
integrin-linked kinase (AF22F1) monoclonal (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0048662 and negative regulation of smooth muscle cell proliferation and biological process this GO :0048812 and neuron projection morphogenesis and biological process this GO :0050772 and positive regulation of axonogenesis and biological process this GO :0050775 and positive regulation of dendrite morphogenesis and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process this GO :2000178 and negative regulation of neural precursor cell proliferation and biological process, HEL-S-28 and ILK-1 and ILK-2 and P59 and p59ILK, ILK and IDBG-29381 and ENSG00000166333 and 3611, ILK and IDBG-634121 and ENSBTAG00000000696 and 540207, Ilk and IDBG-204955 and ENSMUSG00000030890 and 16202, nuclei, this GO :0001558 and regulation of cell growth and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001725 and stress fiber and cellular component this GO :0001954 and positive regulation of cell-matrix adhesion and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007569 and cell aging and biological process this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009966 and regulation of signal transduction and biological process this GO :0010667 and negative regulation of cardiac muscle cell apoptotic process and biological process this GO :0010761 and fibroblast migration and biological process this GO :0014044 and Schwann cell development and biological process this GO :0014912 and negative regulation of smooth muscle cell migration and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004871 : signal transducer activity and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004871 : signal transducer activity, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0017124 : SH3 domain binding, this GO :0019901 : protein kinase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017124 : SH3 domain binding and also this GO :0019901 : protein kinase binding, transferring phosphorus-containing groups and molecular function this GO :0017124 and SH3 domain binding and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0021675 and nerve development and biological process this GO :0022011 and myelination in peripheral nervous system and biological process this GO :0030017 and sarcomere and cellular component this GO :0030027 and lamellipodium and cellular component this GO :0030030 and cell projection organization and biological process this GO :0030054 and cell junction and cellular component this GO :0030335 and positive regulation of cell migration and biological process this GO :0030424 and axon and cellular component this GO :0030513 and positive regulation of BMP signaling pathway and biological process this GO :0032288 and myelin assembly and biological process this GO :0032956 and regulation of actin cytoskeleton organization and biological process this GO :0034329 and cell junction assembly and biological process this GO :0034446 and substrate adhesion-dependent cell spreading and biological process this GO :0042327 and positive regulation of phosphorylation and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043034 and costamere and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043195 and terminal bouton and cellular component this GO :0043198 and dendritic shaft and cellular component this GO :0043206 and extracellular fibril organization and biological process this GO :0043234 and protein complex and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043491 and protein kinase B signaling and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045197 and establishment or maintenance of epithelial cell apical/basal polarity and biological process this GO :0045663 and positive regulation of myoblast differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045773 and positive regulation of axon extension and biological process this GO :0045893 and positive regulation of transcription, integrin-linked kinase |
| Identity: |
6040 |
| Gene: |
ILK |
More about : ILK |
| Long gene name: |
integrin linked kinase |
| Synonyms gene name: |
integrin-linked kinase |
| Locus: |
11p15, 4 |
| Discovery year: |
1997-05-22 |
| GenBank acession: |
U40282 |
| Entrez gene record: |
3611 |
| Pubmed identfication: |
8538749 |
| RefSeq identity: |
NM_004517 |
| Classification: |
Ankyrin repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000133407 |
| Locus Specific Databases: |
LRG_444 |