| Long name: |
Smad2 (7A5) Monoclonal Antibody |
| Also known as: |
Smad2 (7A5) Monoclonal Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Smad2 |
| Specificity: |
This is a highly specific antibody against Smad2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
7A5 |
| Concentration: |
1ug per 1ul |
| Source: |
Recombinant human protein purified from E, coli (His-Smad2) |
| Gene ID number: |
4087 |
| Swiss Prot: |
Q15796 |
| Tested Applications: |
IP, WB |
| Recommended dilutions: |
0 ug), 1 ug/mL) IP (2, WB (0 |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, May act as a tumor suppressor in colorectal carcinoma, Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator, activates transcription, on formation of the SMAD2/SMAD4 complex, Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases |
| Purification method: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
JV18-1, MAD homolog 2, MADH2, MADR2, Mad-related protein 2, Mothers against DPP homolog 2, Mothers against decapentaplegic homolog 2, SMAD 2, SMAD family member 2, Smad2, hMAD-2, hSMAD2, JV18 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
Smad2 (7A5) Monoclonal |
| Short name: |
Smad2 (7A5) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SMAD family member 2 (7A5) monoclonal (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30215 |
| Gene: |
MACC1 |
More about : MACC1 |
| Long gene name: |
MACC1, MET transcriptional regulator |
| Synonyms gene name: |
metastasis associated in colon cancer 1 |
| Synonyms: |
7A5 SH3BP4L |
| Locus: |
7p21, 1 |
| Discovery year: |
2008-10-14 |
| Entrez gene record: |
346389 |
| Pubmed identfication: |
25738887 |
| RefSeq identity: |
NM_182762 |
| Havana BLAST/BLAT: |
OTTHUMG00000128415 |