| Long name: |
Lyn (11A7) Monoclonal Antibody |
| Also known as: |
Lyn (11A7) Monoclonal Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Lyn |
| Specificity: |
This is a highly specific antibody against Lyn |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
11A7 |
| Concentration: |
2ug/ul |
| Source: |
Synthetic peptide |
| Gene ID number: |
4067 |
| Swiss Prot: |
P07948 |
| Tested Applications: |
IP, WB |
| Recommended dilutions: |
0 ug), 0 ug/mL) IP (2, WB (2 |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Blk, Each of these have a common structure consisting of an unique domain at the N-terminal, Fgr, Fyn, Genetic deletion of Lyn results in autoimmunity, Hck, In immume cells, Integrins are major cellular receptor that mediate cell to cell and cell to substratum interactions, Lck, Lyn, Lyn is the predominantly expressed Src-family kinase in B cells and its positive role is done through phosphorylation of the Ig&alpha, SH2 and tyrosine kinase domains, The intracellular protein kinase Lyn participates both positively and negatively in B cell, Yes, and Ig&beta, and Yrk, and generation of hyperactive Lyn results in the same phenotype, followed by SH3, including integrin signaling pathway, mast cell, platelet and myeloid cell signaling, renal disease and premature mortality in mice, revealing the importance of the balance of Lyn signaling, subunits of B cell receptor, the Src-family kinases play roles as critical regulators of a large number of intracellular signaling pathways, The members of the Src-family kinases are Src |
| Purification method: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
LYN, Lck/Yes-related novel protein tyrosine kinase, Tyrosine-protein kinase Lyn, V-yes-1 Yamaguchi sarcoma viral related oncogene homolog, p53Lyn, p56Lyn, JTK8 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
Lyn (11A7) Monoclonal |
| Short name: |
Lyn (11A7) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Lyn (11A7) monoclonal (Antibody to) |
| Alternative technique: |
antibodies |