| Long name: |
Cdc2 (26E11) Monoclonal Antibody |
| Also known as: |
Cdc2 (26E11) Monoclonal Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Cdc2 |
| Specificity: |
This is a highly specific antibody against Cdc2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
2600000000000 |
| Concentration: |
1ug per 1ul |
| Source: |
Recombinant human protein purified from E, coli (His-cdc2) |
| Gene ID number: |
983 |
| Swiss Prot: |
P06493 |
| Tested Applications: |
IP, WB |
| Recommended dilutions: |
0 ug), 5 ug/mL) IP (5, WB (0 |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A Cdk is activated by association with a cyclin, Cdk1, Cdk1, Cdk1 can also enhance cell migration, Cdks are also involved in the regulation of transcription and mRNA processing, Increased levels of Cdk1 promote cell migration together with cyclin B2 and the actin-stabilizing protein caldesmon, Phosphorylation of caldesmon bound to actin results in the displacement of caldesmon from actin followed by the altered interaction of actin with myosin, The Cdk1 protein is constantly present throughout the cell division cycle, These events contribute to increased cell migration, allows a dividing cell to enter into mitosis from G2 and permits the transition from G1 through S in conjunction with cyclin A and cyclin E, also known as cell division control protein 2 (cdc2), but its activity is finely tuned by means of protein-protein interactions and reversible phosphorylation, forming a cyclin-dependent kinase complex, is one of the components of the maturation promoting factor (MPF) which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle, when bound to cyclin B, Cyclin-dependent kinases (cdk) belong to a group of protein kinases originally discovered as being involved in the regulation of the cell cycle |
| Purification method: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CDC28A, CDK1, CDKN1, Cell division control protein 2 homolog, Cell division protein kinase 1, Cyclin-dependent kinase 1, P34CDC2, p34 protein kinase, CDC2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
Cdc2 (26E11) Monoclonal |
| Short name: |
Cdc2 (26E11) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Cdc2 (26E11) monoclonal (Antibody to) |
| Alternative technique: |
antibodies |