| Long name: |
Nitrotyrosine (1F1) Monoclonal Antibody |
| Also known as: |
Nitrotyrosine (1F1) Monoclonal Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Nitrotyroxine |
| Specificity: |
This is a highly specific antibody against Nitrotyroxine |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
1F1 |
| Source: |
Peroxynitrate treated BSA |
| Tested Applications: |
IP, WB |
| Recommended dilutions: |
000) IP (3 ul), WB (1:10 |
| Cross reactivity: |
Others |
| Cross reactive species details: |
Nitrotyrosine |
| Background of the target antigen: |
Nitrotyrosine has been implicated in the pathogenesis of many inflammatory, Nitrotyrosine in the cerebrospinal fluid may be an in vivo marker of oxidative nitric oxide damage, Nitrotyrosine is a relatively stable product formed from various reaction pathways, One of them is the reaction of peroxynitrite with tyrosine, Oxidative stress has been indicated as a mechanism of secondary neuronal injury in traumatic brain injury, Peroxynitrite formed from superoxide and nitric oxide radicals mediates tyrosine nitration reactions on proteins resulting in inactivation of certain house-keeping enzymes as well as endogenous antioxidant enzymes such as catalase and superoxide dismutase, Several pathologies of the cardiovascular system are also associated with an augmented production of nitric oxide and/or superoxide-derived oxidants that lead to nitroxidative stress, The high contents of iron (heme) in certain tissues such as heart and vascular smooth muscle cells could serve as a biological base for iron toxicity on free radical-mediated tissue damage, as well as the production of NO, asthma and a variety of conditions mediated by endothelial injury, atherosclerosis, including formation of nitrotyrosine, infectious and degenerative human diseases such as Alzheimer&rsquo, Nitrotyrosine has been identified as an indicator of cell damage and inflammation, s disease |
| Purification method: |
Ammonium sulfate precipitation |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
Nitrotyrosine (1F1) Monoclonal |
| Short name: |
Nitrotyrosine (1F1) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Nitrotyrosine (1F1) monoclonal (Antibody to) |
| Alternative technique: |
antibodies |