| Long name: |
-chain (52H10) Monoclonal Antibody, Complement C4 &beta |
| Also known as: |
-chain (52H10) Monoclonal Antibody, Complement C4 &beta |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
-chain, Complement C4 &beta |
| Specificity: |
-chain, This is a highly specific antibody against Complement C4 &beta |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
52H10 |
| Concentration: |
2ug/ul |
| Source: |
Protein purified from Human plasma |
| Gene ID number: |
721 |
| Swiss Prot: |
P0C0L4 |
| Tested Applications: |
IF(IHC-P), IHC-P, IP, WB |
| Recommended dilutions: |
0 ug), 0 ug/ml) IP (5, WB (2 |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, C4a anaphylatoxin is a mediator of local inflammatory process, Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes, Derived from proteolytic degradation of complement C4, It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens, Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway |
| Purification method: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Acidic complement C4, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2, C4A, C4B1, C4B12, C4B2, C4B3, C4B5, C4BD, C4B_2, C4F, CO4, CPAMD2, CPAMD3, Complement C4-A, CH |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
-chain (52H10) Monoclonal, Complement C4 &beta |
| Short name: |
-chain (52H10) Monoclonal Antibody, Complement C4 &beta |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
-epitope (52H10) monoclonal (Antibody to), Complement C4 &beta |
| Alternative technique: |
antibodies |