| Long name: |
Erk2 (1A8) Monoclonal Antibody |
| Also known as: |
Erk2 (1A8) Monoclonal Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Erk2 |
| Specificity: |
This is a highly specific antibody against Erk2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
1A8 |
| Concentration: |
1ug per 1ul |
| Source: |
His-tagged recombinant human Erk2 protein purified from E, coli |
| Gene ID number: |
5594 |
| Swiss Prot: |
P28482 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
000), WB (1: 1 |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
MEK1/2, Many different stimuli, Once actived, Raf phosphorylates the other two kinases, Ras interacts with Raf, Upon activation, When growth factors bind to the receptor tyrosine kinase, activate the ERK1 and ERK2 pathways, and activates it as well, and postmitotic functions in differentiated cells, cytokines, including growth factors, ligands for heterotrimeric guanine nucleotide binding protein (G protein)-coupled receptors and transforming agents, mitosis, the ERKs either phosphorylate a number of cytoplasmic targets or migrate to the nucleus, the serine/threonine protein kinase, virus infection, where they phosphorylate and activate a number of transcription factors such as c-Fos and Elk-1, which in turn phosphorylates tyrosine/threonine in ERK 1/2, ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis |
| Purification method: |
Ammonium sulfate precipitation |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ERK-2, ERK2, ERT1, Extracellular signal-regulated kinase 2, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, MAPK 1, MAPK 2, MAPK1, MAPK2, Mitogen-activated protein kinase 1, Mitogen-activated protein kinase 2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, p42-MAPK, ERK |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
Erk2 (1A8) Monoclonal |
| Short name: |
Erk2 (1A8) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Erk2 (1A8) monoclonal (Antibody to) |
| Alternative technique: |
antibodies |