| Long name: |
p38 MAPK (6A1) Monoclonal Antibody |
| Also known as: |
p38 MAPK (6A1) Monoclonal Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
p38 MAPK |
| Specificity: |
This is a highly specific antibody against p38 MAPK |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
6A1 |
| Concentration: |
4ug/ul |
| Source: |
Synthetic Glutaldehyde peptide (KLH coupled) corresponding to C-terminal residues of human p38 MAP kinase |
| Gene ID number: |
1432 |
| Swiss Prot: |
Q16539 |
| Tested Applications: |
WB |
| Recommended dilutions: |
0 ug/ml), WB (4 |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Activated MAPK kinase-3/6 phosphorylate each residue of Thr180 and Tyr182 in p38 MAPK, CHOP-1, MEF-2 and other transcription factors through phosphorylation, Phospho-p38 MAPK activates ATF-2, There are four isoforms of p38 MAPK, When cells are exposed to tumor necrosis factor-, activation of MAPK kinase-3 and &ndash, heat shock, inflammation and other signals, interleukin-1, or other activating stimuli, p38 MAPK is relatively inactive in the non-phosphorylated form and becomes rapidly activated by dual phosphorylation of a Thr-Gly-Tyr motifs, which differ in their tissue expression and affinity for upstream activators and downstream effectors, , , and , 6 occurs by phosphorylation, p38 MAPK cascade regulates a variety of cellular responses to stress |
| Purification method: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CSAID-binding protein, CSBP, CSBP1, CSBP2, CSPB1, Cytokine suppressive anti-inflammatory drug-binding protein, EXIP, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, MAPK 14, MAPK14, MAX-interacting protein 2, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase p38 alpha, Mxi2, PRKM14, PRKM15, SAPK2A, Stress-activated protein kinase 2a, p38, p38ALPHA, RK |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
p38 MAPK (6A1) Monoclonal |
| Short name: |
p38 MAPK (6A1) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
p38 MAPK (6A1) monoclonal (Antibody to) |
| Alternative technique: |
antibodies |