| Also known as: |
MYC / c-Myc |
| Other names: |
Class E basic helix-loop-helix protein 39, Myc proto-oncogene protein, Proto-oncogene c-Myc, Transcription factor p64, avian myelocytomatosis viral oncogene homolog, bHLHe39, class E basic helix-loop-helix protein 39, myc proto-oncogene protein, myc-related translation/localization regulatory factor, proto-oncogene c-Myc, transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog, myc proto-oncogene protein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MYC |
| Gene name synonims: |
c-Myc |
| Other gene names: |
BHLHE39, MRTL, MYC, MYCC, bHLHe39, bHLHe39, c-Myc, MYC |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a, k |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Gorilla, Human (Homo sapiens) <, Monkey, Rat (Rattus norvegicus) (at least 90% immunogen sequence identity), the reactivity of the antibody may extend to other species which are not listed hereby, /b>, Chimpanzee, Orangutan, Predicted Reactivity: <, b> |
| Specificity and cross-reactivity: |
Nuclear protein involved in regulation of cell cycle and apoptosis, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Recognizes C-myc in human nuclear protein |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
0, 1% Sodium Azide, 4), PBS (pH 7 |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius, Store the antibody at +4 degrees Celsius for short term storage |
| Tested applications:: |
ELISA (EIA), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal (IgG2a, k) MYC / c-Myc |
| Short name: |
Mouse Monoclonal (IgG2a, k) MYC / c-Myc Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens v-myc myelocytomatosis viral oncogene homolog (avian) / c-v-myc myelocytomatosis viral oncogene homolog (avian) (Antibody to), Mouse monoclonal (IgG2a, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Bmyc and IDBG-147082 and ENSMUSG00000049086 and 107771, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0006879 and cellular iron ion homeostasis and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0010467 and gene expression and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0015671 and oxygen transport and biological process this GO :0032204 and regulation of telomere maintenance and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032873 and negative regulation of stress-activated MAPK cascade and biological process this GO :0034644 and cellular response to UV and biological process this GO :0035690 and cellular response to drug and biological process this GO :0042493 and response to drug and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0044346 and fibroblast apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045656 and negative regulation of monocyte differentiation and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048147 and negative regulation of fibroblast proliferation and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0051276 and chromosome organization and biological process this GO :0051782 and negative regulation of cell division and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0070491 and repressing transcription factor binding and molecular function this GO :0070848 and response to growth factor and biological process this GO :0070888 and E-box binding and molecular function this GO :0090096 and positive regulation of metanephric cap mesenchymal cell proliferation and biological process this GO :2000573 and positive regulation of DNA biosynthetic process and biological process this GO :2001022 and positive regulation of response to DNA damage stimulus and biological process, E-box binding, MYC and IDBG-35442 and ENSG00000136997 and 4609, MYC and IDBG-644147 and ENSBTAG00000008409 and 511077, bHLHe39 and c-Myc and MRTL and MYCC, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000165 and MAPK cascade and biological process this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0006112 and energy reserve metabolic process and biological process this GO :0006338 and chromatin remodeling and biological process this GO :0006351 and transcription, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0032403 : protein complex binding and also this GO :0046983 : protein dimerization activity and also this GO :0070491 : repressing transcription factor binding and also this GO :0070888 : E-box binding, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0032403 : protein complex binding, this GO :0046983 : protein dimerization activity, this GO :0070491 : repressing transcription factor binding, this GO :0070888 : E-box binding, v-myc myelocytomatosis viral oncogene homolog (avian) |
| Identity: |
7553 |
| Gene: |
MYC |
More about : MYC |
| Long gene name: |
v-myc avian myelocytomatosis viral oncogene homolog |
| Synonyms: |
c-Myc bHLHe39 MYCC |
| Locus: |
8q24, 21 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
4609 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000128475 |