| Also known as: |
MCAM / CD146 |
| Other names: |
CD_antigen: CD146, Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, Gicerin, Melanoma cell adhesion molecule, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen, S-endo 1 endothelial-associated antigen, cell surface glycoprotein MUC18, cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion molecule, melanoma-associated antigen A32, melanoma-associated antigen MUC18, cell surface glycoprotein MUC18 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MCAM |
| Gene name synonims: |
CD146 |
| Other gene names: |
CD146, MCAM, MUC18, MUC18, MCAM |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
6C3E6 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human MCAM / CD146 |
| Purification method: |
Purified |
| Form/Appearance: |
0, 0, 05% sodium azide, 5% protein stabilizer, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Long term Store the antibody at -20 degrees Celsius, Short term Store the antibody at +4 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 6C3E6] (IgG1) MCAM / CD146 |
| Short name: |
Mouse Monoclonal [clone 6C3E6] (IgG1) MCAM / CD146 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens melanoma cell adhesion molecule / CD146 (Antibody to), Mouse monoclonal [clonality 6C3E6] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD146 and MUC18, MCAM and IDBG-631776 and ENSBTAG00000006835 and 281301, MCAM and IDBG-74428 and ENSG00000076706 and 102465453, Mcam and IDBG-155835 and ENSMUSG00000032135 and 84004, nuclei, protein binding, this GO :0003094 and glomerular filtration and biological process this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030335 and positive regulation of cell migration and biological process this GO :0061042 and vascular wound healing and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, 4162, melanoma cell adhesion molecule |
| Identity: |
6934 |
| Gene: |
MCAM |
More about : MCAM |
| Long gene name: |
melanoma cell adhesion molecule |
| Synonyms: |
MUC18 CD146 |
| Synonyms name: |
Gicerin |
| Locus: |
11q23, 3 |
| Discovery year: |
1995-12-18 |
| GenBank acession: |
X68264 |
| Entrez gene record: |
4162 |
| Pubmed identfication: |
2602381 10702685 |
| Classification: |
C2-set domain containing CD molecules V-set domain containing Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166197 |