| Also known as: |
CD135 / FLT3 |
| Other names: |
CD135 antigen, CD_antigen: CD135, FL cytokine receptor, FL cytokine receptor, FLK-2, FLT-3, Fetal liver kinase-2, Fms-like tyrosine kinase 3, Receptor-type tyrosine-protein kinase FLT3, STK-1, STK-1, Stem cell tyrosine kinase 1, fetal liver kinase 2, fms-like tyrosine kinase 3, fms-related tyrosine kinase 3, growth factor receptor tyrosine kinase type III, receptor-type tyrosine-protein kinase FLT3, stem cell tyrosine kinase 1, receptor-type tyrosine-protein kinase FLT3 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD135 |
| Gene name synonims: |
FLT3 |
| Other gene names: |
CD135, CD135, FLK-2, FLK-2, FLK2, FLK2, FLT-3, FLT3, STK-1, STK1, STK1, FLT3 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
BV10A4H2 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Affinity Purified |
| Form/Appearance: |
0, 150 mM sodium chloride, pH 7, 09% sodium azide, 2, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
avoid repeated freeze thaw cycles, Store the antibody at +4 degrees Celsius |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ BV10A4H2] (IgG1) CD135 / FLT3 |
| Short name: |
Mouse Monoclonal [clone BV10A4H2] (IgG1) CD135 / FLT3 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens CD135 / fms-related tyrosine kinase 3 (Antibody to), Mouse monoclonal [clonality BV10A4H2] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CD135 and FLK-2 and FLK2 and STK1, FLT3 and IDBG-19891 and ENSG00000122025 and 2322, Flt3 and IDBG-209045 and ENSMUSG00000042817 and 14255, nuclei, this GO :0001776 and leukocyte homeostasis and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002318 and myeloid progenitor cell differentiation and biological process this GO :0002320 and lymphoid progenitor cell differentiation and biological process this GO :0002328 and pro-B cell differentiation and biological process this GO :0002572 and pro-T cell differentiation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004896 and cytokine receptor activity and molecular function this GO :0005021 and vascular endothelial growth factor-activated receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010243 and response to organonitrogen compound and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0004896 : cytokine receptor activity and also this GO :0005021 : vascular endothelial growth factor-activated receptor activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0004896 : cytokine receptor activity, this GO :0005021 : vascular endothelial growth factor-activated receptor activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0032403 : protein complex binding, this GO :0035259 : glucocorticoid receptor binding, this GO :0042803 : protein homodimerization activity, this GO :0043548 : phosphatidylinositol 3-kinase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0032403 : protein complex binding and also this GO :0035259 : glucocorticoid receptor binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043548 : phosphatidylinositol 3-kinase binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030097 and hemopoiesis and biological process this GO :0030098 and lymphocyte differentiation and biological process this GO :0030183 and B cell differentiation and biological process this GO :0031100 and organ regeneration and biological process this GO :0032403 and protein complex binding and molecular function this GO :0035259 and glucocorticoid receptor binding and molecular function this GO :0035726 and common myeloid progenitor cell proliferation and biological process this GO :0038084 and vascular endothelial growth factor signaling pathway and biological process this GO :0042531 and positive regulation of tyrosine phosphorylation of STAT protein and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043548 and phosphatidylinositol 3-kinase binding and molecular function this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0045578 and negative regulation of B cell differentiation and biological process this GO :0046651 and lymphocyte proliferation and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0071345 and cellular response to cytokine stimulus and biological process this GO :0071385 and cellular response to glucocorticoid stimulus and biological process this GO :0097028 and dendritic cell differentiation and biological process, 28173 and IDBG-630678 and ENSBTAG00000018572 and 512700, fms-related tyrosine kinase 3 |
| Identity: |
3765 |
| Gene: |
FLT3 |
More about : FLT3 |
| Long gene name: |
fms related tyrosine kinase 3 |
| Synonyms gene name: |
fms-related tyrosine kinase 3 |
| Synonyms: |
STK1 FLK2 CD135 |
| Locus: |
13q12, 2 |
| Discovery year: |
1990-07-30 |
| GenBank acession: |
U02687 |
| Entrez gene record: |
2322 |
| Pubmed identfication: |
8394751 |
| Classification: |
CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000016646 |
| Locus Specific Databases: |
LRG_457 |