| Also known as: |
PTPN6 / SHP-1 |
| Other names: |
Hematopoietic cell protein-tyrosine phosphatase, PTP-1C, Protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6, hematopoietic cell phosphatase, hematopoietic cell protein-tyrosine phosphatase, non-receptor type 6, protein tyrosine phosphatase, protein-tyrosine phosphatase 1C, protein-tyrosine phosphatase SHP-1, tyrosine-protein phosphatase non-receptor type 6, tyrosine-protein phosphatase non-receptor type 6 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
PTPN6 |
| Gene name synonims: |
SHP-1 |
| Other gene names: |
HCP, HCP, HCPH, HPTP1C, PTP-1C, PTP-1C, PTP1C, PTPN6, SH-PTP1, SHP-1, SHP-1L, SHP1, PTPN6 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, k |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Ammonium sulfate precipitation |
| Form/Appearance: |
0, 0, and 50% glycerol, 01% BSA, 03% sodium azide, 15M NaCl, HEPES with 0 |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal (IgG1, k) PTPN6 / SHP-1 |
| Short name: |
Mouse Monoclonal (IgG1, k) PTPN6 / SHP-1 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
non-receptor classification 6 / SHP-1 (Antibody to), sapiens protein tyrosine phosphatase, Mouse monoclonal (IgG1, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
HCP and HCPH and HPTP1C and PTP-1C and SH-PTP1 and SHP-1 and SHP-1L and SHP1, PTPN6 and IDBG-15719 and ENSG00000111679 and 5777, PTPN6 and IDBG-640141 and ENSBTAG00000020294 and 512312, Ptpn6 and IDBG-187635 and ENSMUSG00000004266 and 15170, SH2 domain binding, non-receptor type 6, nuclei, this GO :0001784 and phosphotyrosine binding and molecular function this GO :0002244 and hematopoietic progenitor cell differentiation and biological process this GO :0002924 and negative regulation of humoral immune response mediated by circulating immunoglobulin and biological process this GO :0004725 and protein tyrosine phosphatase activity and molecular function this GO :0005001 and transmembrane receptor protein tyrosine phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006470 and protein dephosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016020 and membrane and cellular component this GO :0016311 and dephosphorylation and biological process this GO :0016791 and phosphatase activity and molecular function this GO :0017124 and SH3 domain binding and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030154 and cell differentiation and biological process this GO :0030220 and platelet formation and biological process this GO :0031295 and T cell costimulation and biological process this GO :0033277 and abortive mitotic cell cycle and biological process this GO :0033630 and positive regulation of cell adhesion mediated by integrin and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035855 and megakaryocyte development and biological process this GO :0042105 and alpha-beta T cell receptor complex and cellular component this GO :0042130 and negative regulation of T cell proliferation and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0042267 and natural killer cell mediated cytotoxicity and biological process this GO :0043407 and negative regulation of MAP kinase activity and biological process this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0045087 and innate immune response and biological process this GO :0045577 and regulation of B cell differentiation and biological process this GO :0050732 and negative regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0050859 and negative regulation of B cell receptor signaling pathway and biological process this GO :0050860 and negative regulation of T cell receptor signaling pathway and biological process this GO :0050900 and leukocyte migration and biological process this GO :0051279 and regulation of release of sequestered calcium ion into cytosol and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060334 and regulation of interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070372 and regulation of ERK1 and ERK2 cascade and biological process this GO :0070527 and platelet aggregation and biological process this GO :2000045 and regulation of G1/S transition of mitotic cell cycle and biological process, this GO :0001784 : phosphotyrosine binding, this GO :0001784 : phosphotyrosine binding and also this GO :0004725 : protein tyrosine phosphatase activity and also this GO :0005001 : transmembrane receptor protein tyrosine phosphatase activity and also this GO :0005515 : protein binding and also this GO :0016791 : phosphatase activity and also this GO :0017124 : SH3 domain binding and also this GO :0019901 : protein kinase binding and also this GO :0042169 : SH2 domain binding, this GO :0004725 : protein tyrosine phosphatase activity, this GO :0005001 : transmembrane receptor protein tyrosine phosphatase activity, this GO :0005515 : protein binding, this GO :0016791 : phosphatase activity, this GO :0017124 : SH3 domain binding, this GO :0019901 : protein kinase binding, this GO :0042169 : SH2 domain binding, protein tyrosine phosphatase |
| Identity: |
9658 |
| Gene: |
PTPN6 |
More about : PTPN6 |
| Long gene name: |
non-receptor type 6 , protein tyrosine phosphatase |
| Synonyms: |
HCP HCPH PTP-1C SHP-1 SHP1 |
| Locus: |
12p13, 31 |
| Discovery year: |
1992-02-12 |
| Entrez gene record: |
5777 |
| Pubmed identfication: |
1639416 |
| RefSeq identity: |
NM_002831 |
| Classification: |
Protein tyrosine phosphatases, non-receptor type SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000168518 |