| Also known as: |
MCF2L / DBS |
| Other names: |
DBL's big sister, DBL's big sister, Guanine nucleotide exchange factor DBS, MCF, MCF2 transforming sequence-like protein, MCF2-transforming sequence-like protein, guanine nucleotide exchange factor DBS, 2 cell line derived transforming sequence-like, guanine nucleotide exchange factor DBS isoform b |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MCF2L |
| Gene name synonims: |
DBS |
| Other gene names: |
ARHGEF14, DBS, KIAA0362, MCF2L, OST, MCF2L |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, k |
| Clone: |
1D11 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
Sourced in Ascites, pH 7, 2, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
We strongly recommend to avoid freeze/thaw cycles in order to keep the activity of the antibody maximally unchanged, the antibody should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 1D11] (IgG1, k) MCF2L / DBS |
| Short name: |
Mouse Monoclonal [clone 1D11] (IgG1, k) MCF2L / DBS Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens MCF, 2 cellular line derived transforming sequence-like / DBS (Antibody to), Mouse monoclonal [clonality 1D11] (IgG1, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
1-phosphatidylinositol binding, ARHGEF14 and DBS and OST, Extracellular, MCF2L and IDBG-52007 and ENSG00000126217 and 23263, MCF2L and IDBG-634207 and ENSBTAG00000017289 and, Mcf2l and IDBG-133818 and ENSMUSG00000031442 and 17207, this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005545 and 1-phosphatidylinositol binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007266 and Rho protein signal transduction and biological process this GO :0016020 and membrane and cellular component this GO :0030027 and lamellipodium and cellular component this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0005089 : Rho guanyl-nucleotide exchange factor activity, this GO :0005089 : Rho guanyl-nucleotide exchange factor activity and also this GO :0005515 : protein binding and also this GO :0005545 : 1-phosphatidylinositol binding, this GO :0005515 : protein binding, this GO :0005545 : 1-phosphatidylinositol binding, 2 cell line derived transforming sequence-like, MCF |
| Identity: |
14576 |
| Gene: |
MCF2L |
More about : MCF2L |
| Long gene name: |
MCF, 2 cell line derived transforming sequence like |
| Synonyms: |
KIAA0362 DBS OST ARHGEF14 |
| Locus: |
13q34 |
| Discovery year: |
2001-02-08 |
| GenBank acession: |
AB002360 |
| Entrez gene record: |
23263 |
| Pubmed identfication: |
9205841 |
| Classification: |
Rho guanine nucleotide exchange factors Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000017377 |