| Long name: |
CEA (3G7) Monoclonal Antibody |
| Also known as: |
CEA (3G7) Monoclonal Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CEA |
| Specificity: |
This is a highly specific antibody against CEA |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
3G7 |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CEA/CEACAM5 |
| Gene ID number: |
1048 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members, CEACAM molecules are differentially expressed in epithelial cells or in leucocytes, CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor, It consists of seven CEACAM (CEACAM 1, Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker, The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains, The function of CEACAM family members varies widely: they function as cell adhesion molecules, receptors of Neisseria species and other bacteria, regulators of lymphocyte and dendritic cell activation, tumor suppressors, CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family |
| Purification method: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CD66e, CD66e antigen, CEA, CEACAM 5, CEACAM-5, CEACAM5, Carcinoembryonic antigen, Carcinoembryonic antigen related cell adhesion molecule 5, DKFZp781M2392, Meconium antigen 100, Carcino Embryonic Antigen CEA |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
CEA (3G7) Monoclonal |
| Short name: |
CEA (3G7) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CEA (3G7) monoclonal (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1817 |
| Gene: |
CEACAM5 |
More about : CEACAM5 |
| Long gene name: |
carcinoembryonic antigen related cell adhesion molecule 5 |
| Synonyms gene: |
CEA |
| Synonyms gene name: |
carcinoembryonic antigen-related cell adhesion molecule 5 |
| Synonyms: |
CD66e |
| Locus: |
19q13, 2 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M17303 |
| Entrez gene record: |
1048 |
| RefSeq identity: |
NM_004363 |
| Classification: |
I-set domain containing Immunoglobulin like domain containing CD molecules V-set domain containing Carcinoembryonic antigen related cell adhesion molecule family |
| Havana BLAST/BLAT: |
OTTHUMG00000151061 |