| Also known as: |
GDF15 |
| Other names: |
Growth/differentiation factor 15, MIC-1, Macrophage inhibitory cytokine 1, NAG-1, NRG-1, NRG-1, NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1, NSAID-activated gene 1 protein, NSAID-activated gene 1 protein, NSAID-regulated gene 1 protein, NSAID-regulated gene 1 protein, PTGF-beta, Placental TGF-beta, Placental bone morphogenetic protein, Prostate differentiation factor, growth differentiation factor 15, growth/differentiation factor 15, macrophage inhibitory cytokine 1, placental TGF-beta, placental bone morphogenetic protein, prostate differentiation factor, growth/differentiation factor 15 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
GDF15 |
| Other gene names: |
GDF-15, GDF-15, GDF15, MIC-1, MIC-1, MIC1, MIC1, NAG-1, NAG-1, NRG-1, PDF, PDF, PLAB, PLAB, PTGFB, PTGFB, GDF15 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
6D12, E4, H10 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
A BLAST analysis suggests reactivity with NAG-1 from chimpanzee and macaque based on a 100% homology, Cross-reactivity with NAG-1 from other sources has not been determined, Partial reactivity is expected against rat based on an 86% homology with the immunizing sequence, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, This antibody reacts with the C-terminus of endogenous NAG-1 protein from human tissues |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, 0, pH 7, sterile filtered, 01% sodium azide, 02 M potassium phosphate, 15 M sodium chloride, 2 |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
2 light chains, Each murine monoclonal anibody has his own affinity specific for the clone, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, Monoclonals of this antigen are available in different clones, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Rats are used to make rat monoclonal anti mouse antibodies, Rats , The IgG antibody has 2 , There are 2 heavy chains, There are less rat- than mouse clones however, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, antibodies, antigen , binding sites, genes from rodents , have 4 parts, of the genus , serum |
| Latin name: |
Rattus norvegicus |
| Gene target: |
E4] GDF15, H10, Monoclonal [ 6D12 |
| Short name: |
E4] (IgG) GDF15 Antibody, H10, Monoclonal [clone 6D12 |
| Technique: |
IgGs, Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Host: |
Rat |
| Isotype: |
IgG |
| Species: |
Humans, Rats, Human |
| Alternative name: |
sapiens growth differentiation factor 15 (Antibody to), E4] (Immunoglobulin G) to H, H10, Rat monoclonal [clonality 6D12 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, GDF-15 and MIC-1 and MIC1 and NAG-1 and PDF and PLAB and PTGFB, GDF15 and IDBG-38078 and ENSG00000130513 and 9518, GDF15 and IDBG-641726 and ENSBTAG00000015618 and 618677, Gdf15 and IDBG-163724 and ENSMUSG00000038508 and 23886, growth factor activity, this GO :0005125 and cytokine activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007165 and signal transduction and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008083 and growth factor activity and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity and also this GO :0008083 : growth factor activity, this GO :0008083 : growth factor activity, growth differentiation factor 15 |
| Identity: |
30142 |
| Gene: |
GDF15 |
More about : GDF15 |
| Long gene name: |
growth differentiation factor 15 |
| Synonyms: |
PLAB MIC-1 PDF MIC1 NAG-1 PTGFB |
| Synonyms name: |
prostate differentiation factor |
| Locus: |
19p13, 11 |
| Discovery year: |
2004-02-12 |
| GenBank acession: |
BC008962 |
| Entrez gene record: |
9518 |
| Pubmed identfication: |
11895857 9593718 |
| RefSeq identity: |
NM_004864 |
| Havana BLAST/BLAT: |
OTTHUMG00000183360 |