| Also known as: |
ARRB2 / Beta Arrestin 2 |
| Other names: |
Arrestin beta-2, Beta-arrestin-2, arrestin, arrestin 3, arrestin beta-2, beta 2, beta-arrestin-2, beta-arrestin-2 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ARRB2 |
| Other gene names: |
ARB2, ARB2, ARR2, ARR2, ARRB2, BARR2, ARRB2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a, k |
| Clone: |
3G1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human Beta-Arrestin 2 |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
Sourced in Ascites, pH 7, 2, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing and thawing may destroy the polypeptide chains of the antibodies and should be avoided, For extended periods of time, storage at -80 degrees Celsius is recommended, After aliquoting the antibody should be stored at -20 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or  |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 3G1] (IgG2a, k) ARRB2 / Beta Arrestin 2 |
| Short name: |
Mouse Monoclonal [clone 3G1] (IgG2a, k) ARRB2 / Beta Arrestin 2 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
b 2 / b Arrestin 2 (Antibody to), sapiens arrestin, Mouse monoclonal [clonality 3G1] (IgG2a, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
14-3-3 protein binding, ARB2 and ARR2 and BARR2, ARRB2 and IDBG-19263 and ENSG00000141480 and 409, ARRB2 and IDBG-634360 and ENSBTAG00000035587 and 100851153, Arrb2 and IDBG-194248 and ENSMUSG00000060216 and 216869, beta 2, dopaminergic and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032691 and negative regulation of interleukin-1 beta production and biological process this GO :0032695 and negative regulation of interleukin-12 production and biological process this GO :0032715 and negative regulation of interleukin-6 production and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0032947 and protein complex scaffold and molecular function this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0034122 and negative regulation of toll-like receptor signaling pathway and biological process this GO :0034260 and negative regulation of GTPase activity and biological process this GO :0034392 and negative regulation of smooth muscle cell apoptotic process and biological process this GO :0042699 and follicle-stimulating hormone signaling pathway and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043161 and proteasome-mediated ubiquitin-dependent protein catabolic process and biological process this GO :0043197 and dendritic spine and cellular component this GO :0043422 and protein kinase B binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045211 and postsynaptic membrane and cellular component this GO :0045953 and negative regulation of natural killer cell mediated cytotoxicity and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050965 and detection of temperature stimulus involved in sensory perception of pain and biological process this GO :0051019 and mitogen-activated protein kinase binding and molecular function this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0051928 and positive regulation of calcium ion transport and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0060765 and regulation of androgen receptor signaling pathway and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071889 and 14-3-3 protein binding and molecular function this GO :0090201 and negative regulation of release of cytochrome c from mitochondria and biological process this GO :2000573 and positive regulation of DNA biosynthetic process and biological process, nuclei, this GO :0001664 and G-protein coupled receptor binding and molecular function this GO :0001932 and regulation of protein phosphorylation and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002031 and G-protein coupled receptor internalization and biological process this GO :0002032 and desensitization of G-protein coupled receptor protein signaling pathway by arrestin and biological process this GO :0002092 and positive regulation of receptor internalization and biological process this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005905 and coated pit and cellular component this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006897 and endocytosis and biological process this GO :0007165 and signal transduction and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007420 and brain development and biological process this GO :0007596 and blood coagulation and biological process this GO :0007628 and adult walking behavior and biological process this GO :0008277 and regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0014069 and postsynaptic density and cellular component this GO :0015031 and protein transport and biological process this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0030139 and endocytic vesicle and cellular component this GO :0030168 and platelet activation and biological process this GO :0031397 and negative regulation of protein ubiquitination and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0031623 and receptor internalization and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031691 and alpha-1A adrenergic receptor binding and molecular function this GO :0031692 and alpha-1B adrenergic receptor binding and molecular function this GO :0031701 and angiotensin receptor binding and molecular function this GO :0031702 and type 1 angiotensin receptor binding and molecular function this GO :0031748 and D1 dopamine receptor binding and molecular function this GO :0031762 and follicle-stimulating hormone receptor binding and molecular function this GO :0031826 and type 2A serotonin receptor binding and molecular function this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032226 and positive regulation of synaptic transmission, this GO :0001664 : G-protein coupled receptor binding, this GO :0001664 : G-protein coupled receptor binding and also this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0019899 : enzyme binding and also this GO :0019904 : protein domain specific binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0031691 : alpha-1A adrenergic receptor binding and also this GO :0031692 : alpha-1B adrenergic receptor binding and also this GO :0031701 : angiotensin receptor binding and also this GO :0031702 : type 1 angiotensin receptor binding and also this GO :0031748 : D1 dopamine receptor binding and also this GO :0031762 : follicle-stimulating hormone receptor binding and also this GO :0031826 : type 2A serotonin receptor binding and also this GO :0032403 : protein complex binding and also this GO :0032947 : protein complex scaffold and also this GO :0043422 : protein kinase B binding and also this GO :0051019 : mitogen-activated protein kinase binding and also this GO :0071889 : 14-3-3 protein binding, this GO :0005102 : receptor binding, this GO :0005515 : protein binding, this GO :0019899 : enzyme binding, this GO :0019904 : protein domain specific binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0031691 : alpha-1A adrenergic receptor binding, this GO :0031692 : alpha-1B adrenergic receptor binding, this GO :0031701 : angiotensin receptor binding, this GO :0031702 : type 1 angiotensin receptor binding, this GO :0031748 : D1 dopamine receptor binding, this GO :0031762 : follicle-stimulating hormone receptor binding, this GO :0031826 : type 2A serotonin receptor binding, this GO :0032403 : protein complex binding, this GO :0032947 : protein complex scaffold, this GO :0043422 : protein kinase B binding, this GO :0051019 : mitogen-activated protein kinase binding, this GO :0071889 : 14-3-3 protein binding, 281638, arrestin |
| Identity: |
712 |
| Gene: |
ARRB2 |
More about : ARRB2 |
| Long gene name: |
arrestin beta 2 |
| Synonyms gene: |
ARR2 |
| Synonyms gene name: |
arrestin, beta 2 |
| Synonyms: |
BARR2 DKFZp686L0365 |
| Synonyms name: |
arrestin 3 |
| Locus: |
17p13, 2 |
| Discovery year: |
1994-01-10 |
| Entrez gene record: |
409 |
| Pubmed identfication: |
7695743 |
| RefSeq identity: |
NM_004313 |
| Classification: |
Classical arrestins |
| Havana BLAST/BLAT: |
OTTHUMG00000090759 |