| Also known as: |
BUB1B / BubR1 |
| Other names: |
BUB1 mitotic checkpoint serine/threonine kinase B, MAD3/BUB1-related protein kinase, MAD3/BUB1-related protein kinase, Mitotic checkpoint kinase MAD3L, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Protein SSK1, budding uninhibited by benzimidazoles 1 homolog beta, hBUBR1, mitotic checkpoint kinase MAD3L, mitotic checkpoint serine/threonine-protein kinase BUB1 beta, mitotic checkpoint serine/threonine-protein kinase BUB1 beta |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
BUB1B |
| Gene name synonims: |
BubR1 |
| Other gene names: |
BUB1B, BUB1beta, BUBR1, BUBR1, Bub1A, MAD3L, MAD3L, MVA1, SSK1, SSK1, hBUBR1, hBUBR1, BUB1B |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG, k |
| Clone: |
2G5 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
pH 7, 2, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
We strongly recommend to avoid freeze/thaw cycles in order to keep the activity of the antibody maximally unchanged, the antibody should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested applications:: |
ELISA (EIA), Proximity Ligation Assay, RNA interference, Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
2 light chains, Each murine monoclonal anibody has his own affinity specific for the clone, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, Monoclonals of this antigen are available in different clones, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 2G5] , k) BUB1B / BubR1 |
| Short name: |
Mouse Monoclonal [clone 2G5] (IgG, k) BUB1B / BubR1 Antibody |
| Technique: |
IgGs, Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens budding uninhibited by benzimidazoles 1 homolog b (yeast) / BubR1 (Antibody to), Mouse monoclonal [clonality 2G5] (Immunoglobulin G, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, BUB1B and IDBG-6103 and ENSG00000156970 and 701, Bub1A and BUB1beta and BUBR1 and hBUBR1 and MAD3L and MVA1 and SSK1, Bub1b and IDBG-198179 and ENSMUSG00000040084 and 12236, centromeric region and biological process, nuclei, this GO :0000278 and mitotic cell cycle and biological process this GO :0000776 and kinetochore and cellular component this GO :0000777 and condensed chromosome kinetochore and cellular component this GO :0000778 and condensed nuclear chromosome kinetochore and cellular component this GO :0000940 and condensed chromosome outer kinetochore and cellular component this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005680 and anaphase-promoting complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005815 and microtubule organizing center and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007049 and cell cycle and biological process this GO :0007051 and spindle organization and biological process this GO :0007067 and mitotic nuclear division and biological process this GO :0007091 and metaphase/anaphase transition of mitotic cell cycle and biological process this GO :0007093 and mitotic cell cycle checkpoint and biological process this GO :0007094 and mitotic spindle assembly checkpoint and biological process this GO :0008283 and cell proliferation and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0031145 and anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0034501 and protein localization to kinetochore and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051233 and spindle midzone and cellular component this GO :0051436 and negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051439 and regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0071459 and protein localization to chromosome, 25661 and IDBG-646208 and ENSBTAG00000007237 and 100851213, 537027, budding uninhibited by benzimidazoles 1 homolog beta (yeast) |
| Identity: |
1149 |
| Gene: |
BUB1B |
More about : BUB1B |
| Long gene name: |
BUB1 mitotic checkpoint serine/threonine kinase B |
| Synonyms gene name: |
beta budding uninhibited by benzimidazoles 1 homolog beta (yeast) , budding uninhibited by benzimidazoles 1 (yeast homolog) |
| Synonyms: |
BUBR1 MAD3L Bub1A SSK1 |
| Locus: |
15q15, 1 |
| Discovery year: |
1998-03-25 |
| GenBank acession: |
AF107297 |
| Entrez gene record: |
701 |
| Pubmed identfication: |
9889005 |
| Havana BLAST/BLAT: |
OTTHUMG00000129877 |
| Locus Specific Databases: |
LRG_489 |