| Also known as: |
COL1A1 / Collagen I |
| Other names: |
Alpha-1 type I collagen, Collagen alpha-1(I) chain, alpha 1, alpha-1 chain, alpha-1 type I collagen, collagen, collagen alpha 1 chain type I, collagen alpha-1(I) chain, collagen alpha-1(I) chain, collagen alpha-1(I) chain preproprotein, collagen of skin, pro-alpha-1 collagen type 1, tendon and bone, type I, collagen alpha-1(I) chain preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
COL1A1 |
| Other gene names: |
COL1A1, N/A, OI4, COL1A1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG3, k |
| Clone: |
3G3 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human COL1A1 |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
pH 7, 4, PBS |
| Concentration: |
42 mg/ml |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 3G3] (IgG3, k) COL1A1 / Collagen I |
| Short name: |
Mouse Monoclonal [clone 3G3] (IgG3, k) COL1A1 / Collagen I Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG3 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
a 1 / Collagen I (Antibody to), classification I, sapiens collagen, Mouse monoclonal [clonality 3G3] (IgG3, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
COL1A1 and IDBG-58238 and ENSG00000108821 and 1277, COL1A1 and IDBG-638637 and ENSBTAG00000013103 and 282187, Col1a1 and IDBG-209263 and ENSMUSG00000001506 and 12842, DNA-templated and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048407 and platelet-derived growth factor binding and molecular function this GO :0048545 and response to steroid hormone and biological process this GO :0048705 and skeletal system morphogenesis and biological process this GO :0048706 and embryonic skeletal system development and biological process this GO :0050900 and leukocyte migration and biological process this GO :0051591 and response to cAMP and biological process this GO :0055093 and response to hyperoxia and biological process this GO :0060325 and face morphogenesis and biological process this GO :0060346 and bone trabecula formation and biological process this GO :0060351 and cartilage development involved in endochondral bone morphogenesis and biological process this GO :0070208 and protein heterotrimerization and biological process this GO :0071230 and cellular response to amino acid stimulus and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071300 and cellular response to retinoic acid and biological process this GO :0071306 and cellular response to vitamin E and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071364 and cellular response to epidermal growth factor stimulus and biological process this GO :0071560 and cellular response to transforming growth factor beta stimulus and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process this GO :1902617 and response to fluoride and biological process this GO :1902618 and cellular response to fluoride and biological process, Extracellular, OI4, alpha 1, platelet-derived growth factor binding, this GO :0001501 and skeletal system development and biological process this GO :0001503 and ossification and biological process this GO :0001568 and blood vessel development and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001957 and intramembranous ossification and biological process this GO :0001958 and endochondral ossification and biological process this GO :0005201 and extracellular matrix structural constituent and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005581 and collagen trimer and cellular component this GO :0005584 and collagen type I and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0007584 and response to nutrient and biological process this GO :0007596 and blood coagulation and biological process this GO :0007601 and visual perception and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0009612 and response to mechanical stimulus and biological process this GO :0010718 and positive regulation of epithelial to mesenchymal transition and biological process this GO :0010812 and negative regulation of cell-substrate adhesion and biological process this GO :0015031 and protein transport and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030141 and secretory granule and cellular component this GO :0030168 and platelet activation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030199 and collagen fibril organization and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030574 and collagen catabolic process and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0031667 and response to nutrient levels and biological process this GO :0031960 and response to corticosteroid and biological process this GO :0032355 and response to estradiol and biological process this GO :0032964 and collagen biosynthetic process and biological process this GO :0034504 and protein localization to nucleus and biological process this GO :0034505 and tooth mineralization and biological process this GO :0042060 and wound healing and biological process this GO :0042493 and response to drug and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043434 and response to peptide hormone and biological process this GO :0043588 and skin development and biological process this GO :0043589 and skin morphogenesis and biological process this GO :0044344 and cellular response to fibroblast growth factor stimulus and biological process this GO :0044691 and tooth eruption and biological process this GO :0045893 and positive regulation of transcription, this GO :0005201 : extracellular matrix structural constituent, this GO :0005201 : extracellular matrix structural constituent and also this GO :0005515 : protein binding and also this GO :0042802 : identical protein binding and also this GO :0046872 : metal ion binding and also this GO :0048407 : platelet-derived growth factor binding, this GO :0005515 : protein binding, this GO :0042802 : identical protein binding, this GO :0046872 : metal ion binding, this GO :0048407 : platelet-derived growth factor binding, type I, collagen |
| Identity: |
2197 |
| Gene: |
COL1A1 |
More about : COL1A1 |
| Long gene name: |
collagen type I alpha 1 chain |
| Synonyms gene name: |
alpha 1 , collagen, type I |
| Synonyms: |
OI4 |
| Locus: |
17q21, 33 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
Z74615 |
| Entrez gene record: |
1277 |
| Pubmed identfication: |
3178743 2857713 |
| RefSeq identity: |
NM_000088 |
| Classification: |
Collagens |
| Havana BLAST/BLAT: |
OTTHUMG00000148674 |
| Locus Specific Databases: |
Osteogenesis Imperfecta Variant Database LRG_1 |