| Also known as: |
NOD2 / CARD15 |
| Other names: |
CARD domain containing 2, Caspase recruitment domain-containing protein 15, Inflammatory bowel disease protein 1, NLR family, NOD-like receptor C2, Nucleotide-binding oligomerization domain-containing protein 2, caspase recruitment domain family, caspase recruitment domain protein 15, caspase recruitment domain-containing protein 15, inflammatory bowel disease protein 1, leucine rich repeat and CARD domain containing 2, member 15, nucleotide-binding oligomerization domain, nucleotide-binding oligomerization domain 2, nucleotide-binding oligomerization domain containing 2, nucleotide-binding oligomerization domain-containing protein 2, nucleotide-binding oligomerization domain-containing protein 2 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
NOD2 |
| Other gene names: |
ACUG, BLAU, CARD15, CARD15, CD, CLR16, IBD1, IBD1, NLRC2, NOD2, NOD2B, PSORAS1, 3, NOD2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, k |
| Clone: |
26mNOD2 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Affinity Purified |
| Form/Appearance: |
0, pH 7, 09% sodium azide, 2, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
avoid repeated freeze thaw cycles, Store the antibody at +4 degrees Celsius |
| Tested applications:: |
Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Rats are used to make rat monoclonal anti mouse antibodies, Rats , There are less rat- than mouse clones however, Monoclonals of this antigen are available in different clones, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Rattus norvegicus, Mus musculus |
| Gene target: |
Monoclonal [ 26mNOD2] (IgG1, k) NOD2 / CARD15 |
| Short name: |
Monoclonal [clone 26mNOD2] (IgG1, k) Mouse NOD2 / CARD15 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Host: |
Rat |
| Isotype: |
IgG1 |
| Species: |
Mouses, Rats, Mouse |
| Alternative name: |
Rat monoclonal [clonality 26mNOD2] (IgG1, k) to Mouse nucleotide-binding oli this GO merization domain containing 2 / CARD15 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CARD domain binding, Cell surfaces, NOD2 and IDBG-30654 and ENSG00000167207 and 64127, NOD2 and IDBG-631640 and ENSBTAG00000020936 and 444867, Nod2 and IDBG-179050 and ENSMUSG00000055994 and 257632, leucine rich repeat containing receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0042834 and peptidoglycan binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043234 and protein complex and cellular component this GO :0043330 and response to exogenous dsRNA and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0044130 and negative regulation of growth of symbiont in host and biological process this GO :0045087 and innate immune response and biological process this GO :0045089 and positive regulation of innate immune response and biological process this GO :0045747 and positive regulation of Notch signaling pathway and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0046645 and positive regulation of gamma-delta T cell activation and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050700 and CARD domain binding and molecular function this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0050871 and positive regulation of B cell activation and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051259 and protein oli this GO merization and biological process this GO :0051353 and positive regulation of oxidoreductase activity and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0051770 and positive regulation of nitric-oxide synthase biosynthetic process and biological process this GO :0060585 and positive regulation of prostaglandin-endoperoxide synthase activity and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070423 and nucleotide-binding oli this GO merization domain containing signaling pathway and biological process this GO :0070431 and nucleotide-binding oli this GO merization domain containing 2 signaling pathway and biological process this GO :0071224 and cellular response to peptidoglycan and biological process this GO :0071225 and cellular response to muramyl dipeptide and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071608 and macrophage inflammatory protein-1 alpha production and biological process this GO :0090022 and regulation of neutrophil chemotaxis and biological process this GO :2000110 and negative regulation of macrophage apoptotic process and biological process this GO :2000363 and positive regulation of prostaglandin-E synthase activity and biological process, this GO :0000187 and activation of MAPK activity and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002227 and innate immune response in mucosa and biological process this GO :0002253 and activation of immune response and biological process this GO :0002367 and cytokine production involved in immune response and biological process this GO :0002381 and immunoglobulin production involved in immunoglobulin mediated immune response and biological process this GO :0002606 and positive regulation of dendritic cell antigen processing and presentation and biological process this GO :0002710 and negative regulation of T cell mediated immunity and biological process this GO :0002732 and positive regulation of dendritic cell cytokine production and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0002830 and positive regulation of type 2 immune response and biological process this GO :0002862 and negative regulation of inflammatory response to antigenic stimulus and biological process this GO :0002925 and positive regulation of humoral immune response mediated by circulating immunoglobulin and biological process this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006952 and defense response and biological process this GO :0006963 and positive regulation of antibacterial peptide biosynthetic process and biological process this GO :0006965 and positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria and biological process this GO :0007254 and JNK cascade and biological process this GO :0007584 and response to nutrient and biological process this GO :0008180 and COP9 signalosome and cellular component this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009595 and detection of biotic stimulus and biological process this GO :0009986 and cell surface and cellular component this GO :0016045 and detection of bacterium and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030277 and maintenance of gastrointestinal epithelium and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031982 and vesicle and cellular component this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032494 and response to peptidoglycan and biological process this GO :0032495 and response to muramyl dipeptide and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032498 and detection of muramyl dipeptide and biological process this GO :0032500 and muramyl dipeptide binding and molecular function this GO :0032689 and negative regulation of interferon-gamma production and biological process this GO :0032695 and negative regulation of interleukin-12 production and biological process this GO :0032701 and negative regulation of interleukin-18 production and biological process this GO :0032703 and negative regulation of interleukin-2 production and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0032731 and positive regulation of interleukin-1 beta production and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032740 and positive regulation of interleukin-17 production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0032874 and positive regulation of stress-activated MAPK cascade and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034136 and negative regulation of toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035419 and activation of MAPK activity involved in innate immune response and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0035872 and nucleotide-binding domain, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0019899 : enzyme binding and also this GO :0019901 : protein kinase binding and also this GO :0032500 : muramyl dipeptide binding and also this GO :0042834 : peptidoglycan binding and also this GO :0050700 : CARD domain binding, this GO :0005524 : ATP binding, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0032500 : muramyl dipeptide binding, this GO :0042834 : peptidoglycan binding, this GO :0050700 : CARD domain binding, nucleotide-binding oli this GO merization domain containing 2 |
| Identity: |
5331 |
| Gene: |
NOD2 |
More about : NOD2 |
| Long gene name: |
nucleotide binding oligomerization domain containing 2 |
| Synonyms gene: |
IBD1 CARD15 |
| Synonyms gene name: |
caspase recruitment domain family, member 15 |
| Synonyms: |
BLAU CD PSORAS1 CLR16, 3 NLRC2 |
| Synonyms name: |
CARD domain containing 2 , leucine rich repeat and CARD domain containing 2 NOD-like receptor C2 NLR family, nucleotide-binding oligomerization domain |
| Locus: |
16q12, 1 |
| Discovery year: |
1998-07-10 |
| GenBank acession: |
AF178930 |
| Entrez gene record: |
64127 |
| Pubmed identfication: |
7809109 8587604 |
| RefSeq identity: |
NM_022162 |
| Classification: |
Caspase recruitment domain containing NLR family |
| Havana BLAST/BLAT: |
OTTHUMG00000133171 |
| Locus Specific Databases: |
LRG_177 |