| Also known as: |
CR2 / CD21 |
| Other names: |
CD_antigen: CD21, Complement C3d receptor, Complement receptor type 2, EBV receptor, EBV receptor, Epstein-Barr virus receptor, complement C3d receptor, complement component (3d/Epstein Barr virus) receptor 2, complement receptor type 2, complement receptor type 2 isoform 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CR2 |
| Gene name synonims: |
CD21 |
| Other gene names: |
C3DR, C3DR, CD21, CR, CR2, CVID7, Cr2, EBV receptor, SLEB9, CR2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
Bu32 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
C3dg and iC3b, CD21 is part of the signalling complex that is linked to CD19, CD81 and phosphatidylinositol-3-kinase, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The CD21 molecule acts as a receptor for complement components C3d, This particular antibody might cross react with speacies outside of the listed ones, a 145kD cell surface glycoprotein expressed by mature B lymphocytes, as well as for Epstein Barr Virus, follicular dendritic cells, subsets of normal thymocytes and subsets of T cells, Recognizes human CD21 |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, pH 7, 09% sodium azide, 4, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ Bu32] (IgG1) CR2 / CD21 |
| Short name: |
Mouse Monoclonal [clone Bu32] (IgG1) CR2 / CD21 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens complement component (3d/Epstein Barr virus) receptor 2 / CD21 (Antibody to), Mouse monoclonal [clonality Bu32] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
C3DR and CD21 and CR and CVID7 and SLEB9, CR2 and IDBG-106349 and ENSG00000117322 and 1380, CR2 and IDBG-629275 and ENSBTAG00000038496 and 100335830, Cell surfaces, Cr2 and IDBG-209389 and ENSMUSG00000026616 and 12902, classical pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030183 and B cell differentiation and biological process this GO :0042100 and B cell proliferation and biological process this GO :0042113 and B cell activation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043235 and receptor complex and cellular component this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, protein homodimerization activity, this GO :0001848 and complement binding and molecular function this GO :0002430 and complement receptor mediated signaling pathway and biological process this GO :0003677 and DNA binding and molecular function this GO :0004872 and receptor activity and molecular function this GO :0004875 and complement receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0006958 and complement activation, this GO :0001848 : complement binding, this GO :0001848 : complement binding and also this GO :0003677 : DNA binding and also this GO :0004872 : receptor activity and also this GO :0004875 : complement receptor activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005515 : protein binding and also this GO :0042803 : protein homodimerization activity, this GO :0003677 : DNA binding, this GO :0004872 : receptor activity, this GO :0004875 : complement receptor activity, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005515 : protein binding, this GO :0042803 : protein homodimerization activity, 407126, complement component (3d/Epstein Barr virus) receptor 2 |
| Identity: |
2336 |
| Gene: |
CR2 |
More about : CR2 |
| Long gene name: |
complement C3d receptor 2 |
| Synonyms gene name: |
complement component (3d/Epstein Barr virus) receptor 2 complement component 3d receptor 2 |
| Synonyms: |
CD21 C3DR |
| Synonyms name: |
Epstein-Barr virus receptor |
| Locus: |
1q32, 2 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M26004 |
| Entrez gene record: |
1380 |
| RefSeq identity: |
NM_001877 |
| Classification: |
Sushi domain containing Complement system CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000036307 |
| Locus Specific Databases: |
LRG_348 |