| Also known as: |
NOS3 / eNOS |
| Other names: |
Constitutive NOS, EC-NOS, EC-NOS, Endothelial NOS, NOS type III, NOS type III, NOSIII, NOSIII, Nitric oxide synthase, cNOS, cNOS, constitutive NOS, eNOS, endothelial, endothelial, endothelial NOS, endothelial isoform 1, nitric oxide synthase, nitric oxide synthase 3 (endothelial cell), nitric oxide synthase 3 transcript variant eNOS-delta20, nitric oxide synthase 3 transcript variant eNOS-delta20-21, nitric oxide synthase 3 transcript variant eNOS-delta21, nitric oxide synthase |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
NOS3 |
| Gene name synonims: |
eNOS |
| Other gene names: |
ECNOS, NOS3, NOSIII, cNOS, eNOS, eNOS, NOS3 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
6H2 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human NOS3 |
| Purification method: |
Ascites |
| Form/Appearance: |
0, 03% sodium azide, Ascites fluid |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 6H2] (IgG1) NOS3 / eNOS |
| Short name: |
Mouse Monoclonal [clone 6H2] (IgG1) NOS3 / eNOS Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens nitric oxide synthase 3 (endothelial cell) / eNOS (Antibody to), Mouse monoclonal [clonality 6H2] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ECNOS and eNOS, NADP binding, NOS3 and IDBG-48571 and ENSG00000164867 and 4846, NOS3 and IDBG-637485 and ENSBTAG00000017680 and 287024, Nos3 and IDBG-140461 and ENSMUSG00000028978 and 18127, nuclei, this GO :0000139 and this GO lgi membrane and cellular component this GO :0001525 and angiogenesis and biological process this GO :0001542 and ovulation from ovarian follicle and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001974 and blood vessel remodeling and biological process this GO :0002028 and regulation of sodium ion transport and biological process this GO :0003057 and regulation of the force of heart contraction by chemical signal and biological process this GO :0003100 and regulation of systemic arterial blood pressure by endothelin and biological process this GO :0003785 and actin monomer binding and molecular function this GO :0003958 and NADPH-hemoprotein reductase activity and molecular function this GO :0004517 and nitric-oxide synthase activity and molecular function this GO :0005506 and iron ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005901 and caveola and cellular component this GO :0006527 and arginine catabolic process and biological process this GO :0006809 and nitric oxide biosynthetic process and biological process this GO :0007005 and mitochondrion organization and biological process this GO :0007263 and nitric oxide mediated signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009408 and response to heat and biological process this GO :0010181 and FMN binding and molecular function this GO :0010544 and negative regulation of platelet activation and biological process this GO :0014740 and negative regulation of muscle hyperplasia and biological process this GO :0014806 and smooth muscle hyperplasia and biological process this GO :0016491 and oxidoreductase activity and molecular function this GO :0020037 and heme binding and molecular function this GO :0030324 and lung development and biological process this GO :0030666 and endocytic vesicle membrane and cellular component this GO :0031284 and positive regulation of guanylate cyclase activity and biological process this GO :0031663 and lipopolysaccharide-mediated signaling pathway and biological process this GO :0034405 and response to fluid shear stress and biological process this GO :0034617 and tetrahydrobiopterin binding and molecular function this GO :0034618 and arginine binding and molecular function this GO :0043267 and negative regulation of potassium ion transport and biological process this GO :0043542 and endothelial cell migration and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0045776 and negative regulation of blood pressure and biological process this GO :0045909 and positive regulation of vasodilation and biological process this GO :0046209 and nitric oxide metabolic process and biological process this GO :0046870 and cadmium ion binding and molecular function this GO :0050660 and flavin adenine dinucleotide binding and molecular function this GO :0050661 and NADP binding and molecular function this GO :0050880 and regulation of blood vessel size and biological process this GO :0050999 and regulation of nitric-oxide synthase activity and biological process this GO :0051346 and negative regulation of hydrolase activity and biological process this GO :0051701 and interaction with host and biological process this GO :0051926 and negative regulation of calcium ion transport and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0090382 and pha this GO some maturation and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process, this GO :0003785 : actin monomer binding, this GO :0003785 : actin monomer binding and also this GO :0003958 : NADPH-hemoprotein reductase activity and also this GO :0004517 : nitric-oxide synthase activity and also this GO :0005506 : iron ion binding and also this GO :0005515 : protein binding and also this GO :0005516 : calmodulin binding and also this GO :0010181 : FMN binding and also this GO :0016491 : oxidoreductase activity and also this GO :0020037 : heme binding and also this GO :0034617 : tetrahydrobiopterin binding and also this GO :0034618 : arginine binding and also this GO :0046870 : cadmium ion binding and also this GO :0050660 : flavin adenine dinucleotide binding and also this GO :0050661 : NADP binding, this GO :0003958 : NADPH-hemoprotein reductase activity, this GO :0004517 : nitric-oxide synthase activity, this GO :0005506 : iron ion binding, this GO :0005515 : protein binding, this GO :0005516 : calmodulin binding, this GO :0010181 : FMN binding, this GO :0016491 : oxidoreductase activity, this GO :0020037 : heme binding, this GO :0034617 : tetrahydrobiopterin binding, this GO :0034618 : arginine binding, this GO :0046870 : cadmium ion binding, this GO :0050660 : flavin adenine dinucleotide binding, this GO :0050661 : NADP binding, nitric oxide synthase 3 (endothelial cell) |
| Identity: |
7876 |
| Gene: |
NOS3 |
More about : NOS3 |
| Long gene name: |
nitric oxide synthase 3 |
| Synonyms gene name: |
nitric oxide synthase 3 (endothelial cell) |
| Synonyms: |
ECNOS eNOS |
| Synonyms name: |
endothelial nitric oxide synthase |
| Locus: |
7q36, 1 |
| Discovery year: |
1993-08-23 |
| Entrez gene record: |
4846 |
| Pubmed identfication: |
1379542 |
| RefSeq identity: |
NM_000603 |
| Havana BLAST/BLAT: |
OTTHUMG00000158343 |
| Locus Specific Databases: |
The Globin Gene Server |