| Also known as: |
FLNA / Filamin A |
| Other names: |
ABP-280, Actin-binding protein 280, Alpha-filamin, Endothelial actin-binding protein, Filamin-1, Filamin-A, Non-muscle filamin, actin binding protein 280, alpha, alpha-filamin, endothelial actin-binding protein, filamin A, filamin-1, filamin-A, non-muscle filamin, filamin-A isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
FLNA |
| Other gene names: |
ABP-280, ABP-280, ABPX, CSBS, CVD1, FLN, FLN, FLN-A, FLN-A, FLN1, FLN1, FLNA, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD, FLNA |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, k |
| Clone: |
4E10-1B2 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human FLNA |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
Sourced in Ascites, pH 7, 4, PBS |
| Concentration: |
25 mg/ml |
| Storage and shipping: |
Cycles of freezing and thawing may destroy the polypeptide chains of the antibodies and should be avoided, For extended periods of time, storage at -80 degrees Celsius is recommended, After aliquoting the antibody should be stored at -20 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 4E10-1B2] (IgG1, k) FLNA / Filamin A |
| Short name: |
Mouse Monoclonal [clone 4E10-1B2] (IgG1, k) FLNA / Filamin A Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
alpha / Filamin A (Antibody to), sapiens filamin A, Mouse monoclonal [clonality 4E10-1B2] (IgG1, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ABP-280 and ABPX and CSBS and CVD1 and FLN and FLN-A and FLN1 and FMD and MNS and NHBP and OPD and OPD1 and OPD2 and XLVD and XMVD, FLNA and IDBG-632632 and ENSBTAG00000011190 and 281165, FLNA and IDBG-91003 and ENSG00000196924 and 2316, Flna and IDBG-155134 and ENSMUSG00000031328 and 192176, actin filament binding, alpha, nuclei, this GO :0001837 and epithelial to mesenchymal transition and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0002576 and platelet degranulation and biological process this GO :0003779 and actin binding and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005802 and trans- this GO lgi network and cellular component this GO :0005829 and cytosol and cellular component this GO :0005884 and actin filament and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007195 and adenylate cyclase-inhibiting dopamine receptor signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0015629 and actin cytoskeleton and cellular component this GO :0016020 and membrane and cellular component this GO :0017048 and Rho GTPase binding and molecular function this GO :0017160 and Ral GTPase binding and molecular function this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030168 and platelet activation and biological process this GO :0030863 and cortical cytoskeleton and cellular component this GO :0031267 and small GTPase binding and molecular function this GO :0031523 and Myb complex and cellular component this GO :0031532 and actin cytoskeleton reorganization and biological process this GO :0031852 and mu-type opioid receptor binding and molecular function this GO :0034329 and cell junction assembly and biological process this GO :0034394 and protein localization to cell surface and biological process this GO :0034988 and Fc-gamma receptor I complex binding and molecular function this GO :0042177 and negative regulation of protein catabolic process and biological process this GO :0042384 and cilium assembly and biological process this GO :0042789 and mRNA transcription from RNA polymerase II promoter and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042993 and positive regulation of transcription factor import into nucleus and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043113 and receptor clustering and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043198 and dendritic shaft and cellular component this GO :0043234 and protein complex and cellular component this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045022 and early endosome to late endosome transport and biological process this GO :0045184 and establishment of protein localization and biological process this GO :0046332 and SMAD binding and molecular function this GO :0048365 and Rac GTPase binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050821 and protein stabilization and biological process this GO :0051015 and actin filament binding and molecular function this GO :0051220 and cytoplasmic sequestering of protein and biological process this GO :0051764 and actin crosslink formation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0090307 and spindle assembly involved in mitosis and biological process this GO :0097440 and apical dendrite and cellular component, this GO :0001948 : glycoprotein binding, this GO :0001948 : glycoprotein binding and also this GO :0003779 : actin binding and also this GO :0004871 : signal transducer activity and also this GO :0005080 : protein kinase C binding and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0017048 : Rho GTPase binding and also this GO :0017160 : Ral GTPase binding and also this GO :0031267 : small GTPase binding and also this GO :0031852 : mu-type opioid receptor binding and also this GO :0034988 : Fc-gamma receptor I complex binding and also this GO :0042803 : protein homodimerization activity and also this GO :0044822 : poly(A) RNA binding and also this GO :0046332 : SMAD binding and also this GO :0048365 : Rac GTPase binding and also this GO :0051015 : actin filament binding, this GO :0003779 : actin binding, this GO :0004871 : signal transducer activity, this GO :0005080 : protein kinase C binding, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0017048 : Rho GTPase binding, this GO :0017160 : Ral GTPase binding, this GO :0031267 : small GTPase binding, this GO :0031852 : mu-type opioid receptor binding, this GO :0034988 : Fc-gamma receptor I complex binding, this GO :0042803 : protein homodimerization activity, this GO :0044822 : poly(A) RNA binding, this GO :0046332 : SMAD binding, this GO :0048365 : Rac GTPase binding, this GO :0051015 : actin filament binding, filamin A |
| Identity: |
3754 |
| Gene: |
FLNA |
More about : FLNA |
| Long gene name: |
filamin A |
| Synonyms gene: |
FLN1 FLN OPD2 OPD1 |
| Synonyms gene name: |
alpha , alpha (actin binding protein 280) filamin A, filamin A |
| Synonyms: |
ABP-280 |
| Synonyms name: |
actin binding protein 280 alpha filamin |
| Locus: |
Xq28 |
| Discovery year: |
1993-03-18 |
| GenBank acession: |
X70082 |
| Pubmed identfication: |
8406501 12612583 |
| Havana BLAST/BLAT: |
OTTHUMG00000022712 |
| Locus Specific Databases: |
Mental Retardation database |