| Also known as: |
CTSD / Cathepsin D |
| Other names: |
Cathepsin D, N/A, cathepsin D, cathepsin D, ceroid-lipofuscinosis, epididymis secretory sperm binding protein Li 130P, lysosomal aspartyl peptidase, lysosomal aspartyl protease, neuronal 10, cathepsin D preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CTSD |
| Other gene names: |
CLN10, CPSD, CPSD, CTSD, HEL-S-130P, CTSD |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, k |
| Clone: |
3F12-1B9 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human Cathepsin D |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
Sourced in Ascites, pH 7, 2, PBS |
| Concentration: |
45 mg/ml |
| Storage and shipping: |
Cycles of freezing and thawing may destroy the polypeptide chains of the antibodies and should be avoided, For extended periods of time, storage at -80 degrees Celsius is recommended, After aliquoting the antibody should be stored at -20 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| Gene: |
CTSD |
More about : CTSD |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 3F12-1B9] (IgG1, k) CTSD / Cathepsin D |
| Short name: |
Mouse Monoclonal [clone 3F12-1B9] (IgG1, k) CTSD / Cathepsin D Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens cathepsin D / Cathepsin D (Antibody to), Mouse monoclonal [clonality 3F12-1B9] (IgG1, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CATD and IDBG-645332 and ENSBTAG00000007622 and 282883, CLN10 and CPSD and HEL-S-130P, CTSD and IDBG-19613 and ENSG00000117984 and 1509, Ctsd and IDBG-212523 and ENSMUSG00000007891 and 13033, Extracellular, protein binding, this GO :0004190 and aspartic-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005764 and lysosome and cellular component this GO :0006508 and proteolysis and biological process this GO :0008219 and cell death and biological process this GO :0019886 and antigen processing and presentation of exogenous peptide antigen via MHC class II and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030574 and collagen catabolic process and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0042470 and melanosome and cellular component this GO :0043202 and lysosomal lumen and cellular component this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004190 : aspartic-type endopeptidase activity, this GO :0004190 : aspartic-type endopeptidase activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, cathepsin D |
| Identity: |
2529 |
| Long gene name: |
cathepsin D |
| Synonyms gene: |
CPSD |
| Synonyms gene name: |
cathepsin D (lysosomal aspartyl protease) |
| Synonyms: |
CLN10 |
| Synonyms name: |
ceroid-lipofuscinosis, neuronal 10 |
| Locus: |
11p15, 5 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M11233 |
| Entrez gene record: |
1509 |
| Pubmed identfication: |
3927292 |
| RefSeq identity: |
NM_001909 |
| Classification: |
Cathepsins |
| Havana BLAST/BLAT: |
OTTHUMG00000044760 |
| Locus Specific Databases: |
NCL Mutations , Neuronal Ceroid Lipofuscinoses |