| Also known as: |
ARHGEF11 |
| Other names: |
PDZ-RhoGEF, Rho guanine exchange factor (GEF) 11, Rho guanine nucleotide exchange factor (GEF) 11, Rho guanine nucleotide exchange factor 11, RhoA-specific guanine nucleotide exchange factor, RhoGEF glutamate transport modulator, glutamate transporter EAAT4-associated protein 48, rho guanine nucleotide exchange factor 11, rho guanine nucleotide exchange factor 11 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ARHGEF11 |
| Other gene names: |
ARHGEF11, GTRAP48, KIAA0380, PDZ-RHOGEF, ARHGEF11 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, k |
| Clone: |
2H7 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human ARHGEF11 |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
Sourced in Ascites, pH 7, 2, PBS |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or  |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 2H7] (IgG1, k) ARHGEF11 |
| Short name: |
Mouse Monoclonal [clone 2H7] (IgG1, k) ARHGEF11 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens Rho guanine nucleotide exchange factor (GEF) 11 (Antibody to), Mouse monoclonal [clonality 2H7] (IgG1, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ARHGEF11 and IDBG-103650 and ENSG00000132694 and 9826, ARHGEF11 and IDBG-631202 and ENSBTAG00000012361 and 511220, Arhgef11 and IDBG-157390 and ENSMUSG00000041977 and 213498, DNA-templated and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0097190 and apoptotic signaling pathway and biological process, GTRAP48 and PDZ-RHOGEF, Plasma membranes, protein binding, this GO :0000910 and cytokinesis and biological process this GO :0001558 and regulation of cell growth and biological process this GO :0001664 and G-protein coupled receptor binding and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005096 and GTPase activator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006928 and cellular component movement and biological process this GO :0006941 and striated muscle contraction and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007266 and Rho protein signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0008277 and regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0016020 and membrane and cellular component this GO :0030010 and establishment of cell polarity and biological process this GO :0030036 and actin cytoskeleton organization and biological process this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0038032 and termination of G-protein coupled receptor signaling pathway and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045893 and positive regulation of transcription, this GO :0001664 : G-protein coupled receptor binding, this GO :0001664 : G-protein coupled receptor binding and also this GO :0005089 : Rho guanyl-nucleotide exchange factor activity and also this GO :0005096 : GTPase activator activity and also this GO :0005515 : protein binding, this GO :0005089 : Rho guanyl-nucleotide exchange factor activity, this GO :0005096 : GTPase activator activity, this GO :0005515 : protein binding, Rho guanine nucleotide exchange factor (GEF) 11 |
| Identity: |
14580 |
| Gene: |
ARHGEF11 |
More about : ARHGEF11 |
| Long gene name: |
Rho guanine nucleotide exchange factor 11 |
| Synonyms gene name: |
Rho guanine nucleotide exchange factor (GEF) 11 |
| Synonyms: |
KIAA0380 GTRAP48 PDZ-RHOGEF |
| Locus: |
1q23, 1 |
| Discovery year: |
2001-02-08 |
| GenBank acession: |
AB002378 |
| Entrez gene record: |
9826 |
| Pubmed identfication: |
10526156 9205841 |
| RefSeq identity: |
NM_198236 |
| Classification: |
Rho guanine nucleotide exchange factors PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000041292 |