| Also known as: |
SERPING1 / C1 Inhibitor |
| Other names: |
C1 esterase inhibitor, C1 esterase inhibitor, C1-inhibiting factor, C1-inhibiting factor, Plasma protease C1 inhibitor, Serpin G1, clade G (C1 inhibitor), complement component 1 inhibitor, member 1, plasma protease C1 inhibitor, serine/cysteine proteinase inhibitor clade G member 1, serpin G1, serpin peptidase inhibitor, plasma protease C1 inhibitor |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
SERPING1 |
| Other gene names: |
C1 Inh, C1IN, C1IN, C1INH, C1Inh, C1NH, C1NH, HAE1, HAE2, SERPING1, SERPING1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a, k |
| Clone: |
3F4-1D9 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human SERPING1 |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
pH 7, 4, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Cycles of freezing and thawing may destroy the polypeptide chains of the antibodies and should be avoided, For extended periods of time, storage at -80 degrees Celsius is recommended, After aliquoting the antibody should be stored at -20 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 3F4-1D9] (IgG2a, k) SERPING1 / C1 Inhibitor |
| Short name: |
Mouse Monoclonal [clone 3F4-1D9] (IgG2a, k) SERPING1 / C1 Inhibitor Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
clade G (C1 inhibitor), member 1 / C1 suppressor (Antibody to), sapiens serpin peptidase inhibitor, Mouse monoclonal [clonality 3F4-1D9] (IgG2a, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, C1IN and C1INH and C1NH and HAE1 and HAE2, Extracellular, SERPING1 and IDBG-46853 and ENSG00000149131 and 710, Serping1 and IDBG-185264 and ENSMUSG00000023224 and 12258, clade G (C1 inhibitor), classical pathway and biological process this GO :0007568 and aging and biological process this GO :0007596 and blood coagulation and biological process this GO :0007597 and blood coagulation, intrinsic pathway and biological process this GO :0008015 and blood circulation and biological process this GO :0008233 and peptidase activity and molecular function this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0030168 and platelet activation and biological process this GO :0030193 and regulation of blood coagulation and biological process this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0042730 and fibrinolysis and biological process this GO :0045087 and innate immune response and biological process this GO :0045916 and negative regulation of complement activation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072562 and blood microparticle and cellular component, lectin pathway and biological process this GO :0002576 and platelet degranulation and biological process this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006508 and proteolysis and biological process this GO :0006958 and complement activation, member 1, peptidase activity, this GO :0001869 and negative regulation of complement activation, this GO :0004867 : serine-type endopeptidase inhibitor activity, this GO :0004867 : serine-type endopeptidase inhibitor activity and also this GO :0005515 : protein binding and also this GO :0008233 : peptidase activity, this GO :0005515 : protein binding, this GO :0008233 : peptidase activity, 22969 and IDBG-637881 and ENSBTAG00000016267 and 281035, serpin peptidase inhibitor |
| Identity: |
1228 |
| Gene: |
SERPING1 |
More about : SERPING1 |
| Long gene name: |
serpin family G member 1 |
| Synonyms gene: |
C1NH |
| Synonyms gene name: |
(angioedema, clade G (C1 inhibitor), clade G (C1 inhibitor), hereditary) serpin peptidase inhibitor, member 1, member 1 , serine (or cysteine) proteinase inhibitor |
| Synonyms: |
C1IN C1-INH HAE1 HAE2 |
| Synonyms name: |
hereditary , plasma protease C1 inhibitor angioedema |
| Locus: |
11q12, 1 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
X54486 |
| Entrez gene record: |
710 |
| Pubmed identfication: |
2026152 24172014 |
| RefSeq identity: |
NM_000062 |
| Classification: |
Serpin peptidase inhibitors |
| Havana BLAST/BLAT: |
OTTHUMG00000150304 |
| Locus Specific Databases: |
SERPING1base: Mutation registry for Hereditary angioedema LRG_105 |