| Also known as: |
CCND1 / Cyclin D1 |
| Other names: |
B-cell CLL/lymphoma 1, B-cell lymphoma 1 protein, B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL-1 oncogene, G1/S-specific cyclin-D1, G1/S-specific cyclin-D1, PRAD1 oncogene, PRAD1 oncogene, cyclin D1, G1/S-specific cyclin-D1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CCND1 |
| Other gene names: |
BCL-1, BCL1, BCL1, CCND1, D11S287E, PRAD1, PRAD1, U21B31, CCND1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
1, CD1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, an ubiquitously expressed 33 kD protein that migrates as a 36 kD band under reducing SDS-PAGE conditions, 1 recognizes cyclin D1, The antibody CD1 |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
15 mM sodium azide, pH 7, 4, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
ELISA (EIA), Flow Cytometry (FC/FACS), IHC - Frozen), Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
1] (IgG1) CCND1 / Cyclin D1, Monoclonal [ CD1 |
| Short name: |
1] (IgG1) CCND1 / Cyclin D1 Antibody, Mouse Monoclonal [clone CD1 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens cyclin D1 / Cyclin D1 (Antibody to), 1] (IgG1) to H, Mouse monoclonal [clonality CD1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BCL1 and D11S287E and PRAD1 and U21B31, CCND1 and IDBG-61868 and ENSG00000110092 and 595, CCND1 and IDBG-645012 and ENSBTAG00000017514 and 524530, Ccnd1 and IDBG-212973 and ENSMUSG00000070348 and 12443, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007049 and cell cycle and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007595 and lactation and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0010033 and response to organic substance and biological process this GO :0010039 and response to iron ion and biological process this GO :0010165 and response to X-ray and biological process this GO :0010243 and response to organonitrogen compound and biological process this GO :0010971 and positive regulation of G2/M transition of mitotic cell cycle and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016020 and membrane and cellular component this GO :0016055 and Wnt signaling pathway and biological process this GO :0016301 and kinase activity and molecular function this GO :0016538 and cyclin-dependent protein serine/threonine kinase regulator activity and molecular function this GO :0017053 and transcriptional repressor complex and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030857 and negative regulation of epithelial cell differentiation and biological process this GO :0030968 and endoplasmic reticulum unfolded protein response and biological process this GO :0031100 and organ regeneration and biological process this GO :0031571 and mitotic G1 DNA damage checkpoint and biological process this GO :0032026 and response to magnesium ion and biological process this GO :0032403 and protein complex binding and molecular function this GO :0033197 and response to vitamin E and biological process this GO :0033327 and Leydig cell differentiation and biological process this GO :0033598 and mammary gland epithelial cell proliferation and biological process this GO :0033601 and positive regulation of mammary gland epithelial cell proliferation and biological process this GO :0042493 and response to drug and biological process this GO :0042826 and histone deacetylase binding and molecular function this GO :0043627 and response to estrogen and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0045471 and response to ethanol and biological process this GO :0045737 and positive regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0048545 and response to steroid hormone and biological process this GO :0051301 and cell division and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0051412 and response to corticosterone and biological process this GO :0051592 and response to calcium ion and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060749 and mammary gland alveolus development and biological process this GO :0070064 and proline-rich region binding and molecular function this GO :0070141 and response to UV-A and biological process this GO :0071157 and negative regulation of cell cycle arrest and biological process this GO :0071310 and cellular response to organic substance and biological process this GO :2000045 and regulation of G1/S transition of mitotic cell cycle and biological process, nuclei, proline-rich region binding, this GO :0000079 and regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000307 and cyclin-dependent protein kinase holoenzyme complex and cellular component this GO :0000320 and re-entry into mitotic cell cycle and biological process this GO :0001889 and liver development and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0003714 and transcription corepressor activity and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005923 and tight junction and cellular component this GO :0006351 and transcription, this GO :0003714 : transcription corepressor activity, this GO :0003714 : transcription corepressor activity and also this GO :0004672 : protein kinase activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0016301 : kinase activity and also this GO :0016538 : cyclin-dependent protein serine/threonine kinase regulator activity and also this GO :0019899 : enzyme binding and also this GO :0019901 : protein kinase binding and also this GO :0032403 : protein complex binding and also this GO :0042826 : histone deacetylase binding and also this GO :0070064 : proline-rich region binding, this GO :0004672 : protein kinase activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0016301 : kinase activity, this GO :0016538 : cyclin-dependent protein serine/threonine kinase regulator activity, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0032403 : protein complex binding, this GO :0042826 : histone deacetylase binding, this GO :0070064 : proline-rich region binding, cyclin D1 |
| Identity: |
1582 |
| Gene: |
CCND1 |
More about : CCND1 |
| Long gene name: |
cyclin D1 |
| Synonyms gene: |
BCL1 D11S287E PRAD1 |
| Synonyms gene name: |
cyclin D1 (PRAD1: parathyroid adenomatosis 1) |
| Synonyms: |
U21B31 |
| Synonyms name: |
parathyroid adenomatosis 1 B-cell CLL/lymphoma 1 G1/S-specific cyclin D1 |
| Locus: |
11q13, 3 |
| Discovery year: |
1991-06-06 |
| GenBank acession: |
Z23022 |
| Entrez gene record: |
595 |
| Pubmed identfication: |
1826542 1833066 |
| RefSeq identity: |
NM_053056 |
| Classification: |
Cyclins |
| Havana BLAST/BLAT: |
OTTHUMG00000167877 |
| Locus Specific Databases: |
LRG_990 |