| Also known as: |
VLDLR |
| Other names: |
N/A, VLDL receptor, VLDL-R, Very low-density lipoprotein receptor, very low density lipoprotein receptor, very low-density lipoprotein receptor, very low-density lipoprotein receptor isoform a |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
VLDLR |
| Other gene names: |
CARMQ1, CHRMQ1, VLDL receptor, VLDL-R, VLDLR, VLDLRCH, VLDLR |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1, k |
| Clone: |
1H10 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Binds to an epitope on the C-terminus of the ligand binding domain (aa191-355) of VLDL receptor and blocks apoE4 binding |
| Purification method: |
Purified IgG |
| Form/Appearance: |
0, 1mM EDTA, Sourced in TCS, pH 6, 05M Sodium Phosphate, 1M NaCl, 6 |
| Concentration: |
2 mg/ml |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, It is recommended to minimize such cycles as much as possible, the antibody should be stored at -70 or -80 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 1H10] (IgG1, k) VLDLR |
| Short name: |
Mouse Monoclonal [clone 1H10] (IgG1, k) VLDLR Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens very low density lipoprotein receptor (Antibody to), Mouse monoclonal [clonality 1H10] (IgG1, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CARMQ1 and CHRMQ1 and VLDLRCH, Extracellular, VLDLR and IDBG-44752 and ENSG00000147852 and 7436, VLDLR and IDBG-631615 and ENSBTAG00000018517 and 282123, Vldlr and IDBG-155959 and ENSMUSG00000024924 and 22359, calcium-dependent protein binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0005041 and low-density lipoprotein receptor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005905 and coated pit and cellular component this GO :0006869 and lipid transport and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007165 and signal transduction and biological process this GO :0007399 and nervous system development and biological process this GO :0007613 and memory and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0021517 and ventral spinal cord development and biological process this GO :0030229 and very-low-density lipoprotein particle receptor activity and molecular function this GO :0034185 and apolipoprotein binding and molecular function this GO :0034189 and very-low-density lipoprotein particle binding and molecular function this GO :0034361 and very-low-density lipoprotein particle and cellular component this GO :0034436 and glycoprotein transport and biological process this GO :0034437 and glycoprotein transporter activity and molecular function this GO :0034447 and very-low-density lipoprotein particle clearance and biological process this GO :0038025 and reelin receptor activity and molecular function this GO :0038026 and reelin-mediated signaling pathway and biological process this GO :0043235 and receptor complex and cellular component this GO :0045087 and innate immune response and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0048306 and calcium-dependent protein binding and molecular function this GO :1900006 and positive regulation of dendrite development and biological process, this GO :0001948 : glycoprotein binding, this GO :0001948 : glycoprotein binding and also this GO :0005041 : low-density lipoprotein receptor activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0030229 : very-low-density lipoprotein particle receptor activity and also this GO :0034185 : apolipoprotein binding and also this GO :0034189 : very-low-density lipoprotein particle binding and also this GO :0034437 : glycoprotein transporter activity and also this GO :0038025 : reelin receptor activity and also this GO :0048306 : calcium-dependent protein binding, this GO :0005041 : low-density lipoprotein receptor activity, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0030229 : very-low-density lipoprotein particle receptor activity, this GO :0034185 : apolipoprotein binding, this GO :0034189 : very-low-density lipoprotein particle binding, this GO :0034437 : glycoprotein transporter activity, this GO :0038025 : reelin receptor activity, this GO :0048306 : calcium-dependent protein binding, very low density lipoprotein receptor |
| Identity: |
12698 |
| Gene: |
VLDLR |
More about : VLDLR |
| Long gene name: |
very low density lipoprotein receptor |
| Synonyms: |
CARMQ1 CHRMQ1 VLDLRCH |
| Locus: |
9p24, 2 |
| Discovery year: |
1993-09-24 |
| Entrez gene record: |
7436 |
| Pubmed identfication: |
8294473 |
| RefSeq identity: |
NM_003383 |
| Classification: |
Low density lipoprotein receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000019447 |