| Also known as: |
HDAC3 |
| Other names: |
Histone deacetylase 3, RPD3-2, SMAP45, SMAP45, histone deacetylase 3, histone deacetylase 3, histone deacetylase 3 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
HDAC3 |
| Other gene names: |
HD3, HD3, HDAC3, RPD3, RPD3-2, HDAC3 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
7G6C5 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human HDAC3 |
| Purification method: |
Ascites |
| Form/Appearance: |
0, 03% sodium azide, Ascites fluid |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
ELISA (EIA), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 7G6C5] (IgG2a) HDAC3 |
| Short name: |
Mouse Monoclonal [clone 7G6C5] (IgG2a) HDAC3 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens histone deacetylase 3 (Antibody to), Mouse monoclonal [clonality 7G6C5] (IgG2a) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006476 and protein deacetylation and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007346 and regulation of mitotic cell cycle and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008152 and metabolic process and biological process this GO :0016568 and chromatin modification and biological process this GO :0016575 and histone deacetylation and biological process this GO :0016787 and hydrolase activity and molecular function this GO :0017053 and transcriptional repressor complex and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030332 and cyclin binding and molecular function this GO :0031490 and chromatin DNA binding and molecular function this GO :0032041 and NAD-dependent histone deacetylase activity (H3-K14 specific) and molecular function this GO :0032922 and circadian regulation of gene expression and biological process this GO :0033558 and protein deacetylase activity and molecular function this GO :0040014 and regulation of multicellular organism growth and biological process this GO :0042826 and histone deacetylase binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0046329 and negative regulation of JNK cascade and biological process this GO :0046969 and NAD-dependent histone deacetylase activity (H3-K9 specific) and molecular function this GO :0046970 and NAD-dependent histone deacetylase activity (H4-K16 specific) and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051225 and spindle assembly and biological process this GO :0070932 and histone H3 deacetylation and biological process this GO :0070933 and histone H4 deacetylation and biological process this GO :0097372 and NAD-dependent histone deacetylase activity (H3-K18 specific) and molecular function, HD3 and RPD3 and RPD3-2, HDAC3 and IDBG-50725 and ENSG00000171720 and 8841, HDAC3 and IDBG-646121 and ENSBTAG00000017360 and 404125, Hdac3 and IDBG-140814 and ENSMUSG00000024454 and 15183, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, this GO :0000118 and histone deacetylase complex and cellular component this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0004407 and histone deacetylase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005876 and spindle microtubule and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003714 : transcription corepressor activity and also this GO :0004407 : histone deacetylase activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0016787 : hydrolase activity and also this GO :0019899 : enzyme binding and also this GO :0030332 : cyclin binding and also this GO :0031490 : chromatin DNA binding and also this GO :0032041 : NAD-dependent histone deacetylase activity (H3-K14 specific) and also this GO :0033558 : protein deacetylase activity and also this GO :0042826 : histone deacetylase binding and also this GO :0046969 : NAD-dependent histone deacetylase activity (H3-K9 specific) and also this GO :0046970 : NAD-dependent histone deacetylase activity (H4-K16 specific) and also this GO :0097372 : NAD-dependent histone deacetylase activity (H3-K18 specific), this GO :0003682 : chromatin binding, this GO :0003714 : transcription corepressor activity, this GO :0004407 : histone deacetylase activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0016787 : hydrolase activity, this GO :0019899 : enzyme binding, this GO :0030332 : cyclin binding, this GO :0031490 : chromatin DNA binding, this GO :0032041 : NAD-dependent histone deacetylase activity (H3-K14 specific), this GO :0033558 : protein deacetylase activity, this GO :0042826 : histone deacetylase binding, this GO :0046969 : NAD-dependent histone deacetylase activity (H3-K9 specific), this GO :0046970 : NAD-dependent histone deacetylase activity (H4-K16 specific), this GO :0097372 : NAD-dependent histone deacetylase activity (H3-K18 specific), histone deacetylase 3 |
| Identity: |
4854 |
| Gene: |
HDAC3 |
More about : HDAC3 |
| Long gene name: |
histone deacetylase 3 |
| Synonyms: |
RPD3 HD3 RPD3-2 |
| Locus: |
5q31, 3 |
| Discovery year: |
1999-01-29 |
| GenBank acession: |
AF059650 |
| Entrez gene record: |
8841 |
| Pubmed identfication: |
9501169 9464271 |
| RefSeq identity: |
NM_003883 |
| Classification: |
Histone deacetylases, class I |
| Havana BLAST/BLAT: |
OTTHUMG00000129629 |