| Also known as: |
CASP7 / Caspase 7 |
| Other names: |
Apoptotic protease Mch-3, CMH-1, Caspase-7, ICE-LAP3, ICE-like apoptotic protease 3, ICE-like apoptotic protease 3, apoptosis-related cysteine peptidase, apoptosis-related cysteine protease, apoptotic protease MCH-3, caspase 7, caspase 7, caspase-7, caspase-7 isoform alpha |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CASP7 |
| Other gene names: |
CASP-7, CASP-7, CASP7, CMH-1, ICE-LAP3, ICE-LAP3, LICE2, MCH3, MCH3, CASP7 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
22920 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Human (Homo sapiens), Monkey, Mouse (Mus musculus), Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Hamster |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This antibody recognizes recombinant caspase-7 as well as full length pro-caspase-7 and processed enzyme from apoptotic Jurkat cell lysates, This particular antibody might cross react with speacies outside of the listed ones, corresponding to the apparent molecular mass of the caspase-7 on SDS-PAGE immunoblots, in samples from human, monkey and hamster origins, mouse, rat, Detects an ~37 kD protein |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, 50 mM sodium chloride, pH 7, 1 mM PMSF), 2, PBS (10 mM sodium phosphate |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, For maximum product recovery, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, after thawing, centrifuge the product vial before removing cap, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
2 light chains, Each murine monoclonal anibody has his own affinity specific for the clone, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, Monoclonals of this antigen are available in different clones, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 10-1-62] CASP7 / Caspase 7 |
| Short name: |
Mouse Monoclonal [clone 10-1-62] (IgG) CASP7 / Caspase 7 Antibody |
| Technique: |
IgGs, Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
apoptosis-related cysteine peptidase / caspase 7 (Antibody to), sapiens caspase 7, Mouse monoclonal [clonality 10-1-62] (Immunoglobulin G) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CASP-7 and CMH-1 and ICE-LAP3 and LICE2 and MCH3, CASP7 and IDBG-90066 and ENSG00000165806 and 840, Casp7 and IDBG-178813 and ENSMUSG00000025076 and 12369, apoptosis-related cysteine peptidase, cysteine-type endopeptidase activity involved in apoptotic process, nuclei, this GO :0001836 and release of cytochrome c from mitochondria and biological process this GO :0004190 and aspartic-type endopeptidase activity and molecular function this GO :0004197 and cysteine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006508 and proteolysis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0007507 and heart development and biological process this GO :0007568 and aging and biological process this GO :0008234 and cysteine-type peptidase activity and molecular function this GO :0008635 and activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c and biological process this GO :0009411 and response to UV and biological process this GO :0016485 and protein processing and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0097153 and cysteine-type endopeptidase activity involved in apoptotic process and molecular function this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :0097194 and execution phase of apoptosis and biological process, this GO :0004190 : aspartic-type endopeptidase activity, this GO :0004190 : aspartic-type endopeptidase activity and also this GO :0004197 : cysteine-type endopeptidase activity and also this GO :0005515 : protein binding and also this GO :0008234 : cysteine-type peptidase activity and also this GO :0097153 : cysteine-type endopeptidase activity involved in apoptotic process, this GO :0004197 : cysteine-type endopeptidase activity, this GO :0005515 : protein binding, this GO :0008234 : cysteine-type peptidase activity, this GO :0097153 : cysteine-type endopeptidase activity involved in apoptotic process, 62821 and IDBG-639904 and ENSBTAG00000006615 and 526279, caspase 7 |
| Identity: |
1508 |
| Gene: |
CASP7 |
More about : CASP7 |
| Long gene name: |
caspase 7 |
| Synonyms gene name: |
apoptosis-related cysteine peptidase , apoptosis-related cysteine protease caspase 7, caspase 7 |
| Synonyms: |
MCH3 CMH-1 ICE-LAP3 |
| Locus: |
10q25, 3 |
| Discovery year: |
1996-07-22 |
| GenBank acession: |
U37448 |
| Entrez gene record: |
840 |
| Pubmed identfication: |
8521391 8576161 |
| RefSeq identity: |
NM_033338 |
| Classification: |
Caspases |
| Havana BLAST/BLAT: |
OTTHUMG00000019076 |