| Also known as: |
Melanoma Antigen NKI/C3 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
NKI/C3 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Cross-reactivity: The antibody reacts with some mucus producing tumors, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The antigen has a 25 kD unglycosylated precursor in formalin fixed and paraffin-embedded tissue sections, This particular antibody might cross react with speacies outside of the listed ones, bronchial glands, carcinoids, carcinomas of the thyroid, histiocytes in tumor regions and with cells with secretory functions such as salivary glands, mast cells, pancreas and prostate, sweat glands, This antibody recognizes a heterogeneous 25-110 kD glycoprotein that is located mainly in the inner side of membranes of cytoplasmic vesicles in melanoma cells |
| Purification method: |
Ascites |
| Form/Appearance: |
1% BSA, 15 mM sodium azide, 50 mM PBS at, pH 7, 4, Ascites |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ NKI/C3] (IgG1) Melanoma NKI/C3 |
| Short name: |
Mouse Monoclonal [clone NKI/C3] (IgG1) Melanoma Antigen NKI/C3 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens Melanoma protein NKI/complement component 3 (Antibody to), Mouse monoclonal [clonality NKI/complement component 3] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AHUS5 and ARMD9 and ASP and C3a and C3b and CPAMD1 and HEL-S-62p, BT, C3 and IDBG-193788 and ENSMUSG00000024164 and 102642251, C3 and IDBG-21798 and ENSG00000125730 and 718, C5L2 anaphylatoxin chemotactic receptor binding, Extracellular, alternative pathway and biological process this GO :0006958 and complement activation, classical pathway and biological process this GO :0007165 and signal transduction and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0010575 and positive regulation vascular endothelial growth factor production and biological process this GO :0010828 and positive regulation of glucose transport and biological process this GO :0010866 and regulation of triglyceride biosynthetic process and biological process this GO :0010884 and positive regulation of lipid storage and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0031715 and C5L2 anaphylatoxin chemotactic receptor binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045745 and positive regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0050776 and regulation of immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072562 and blood microparticle and cellular component this GO :2000427 and positive regulation of apoptotic cell clearance and biological process, this GO :0001798 and positive regulation of type IIa hypersensitivity and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001970 and positive regulation of activation of membrane attack complex and biological process this GO :0004866 and endopeptidase inhibitor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006631 and fatty acid metabolic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0006956 and complement activation and biological process this GO :0006957 and complement activation, this GO :0004866 : endopeptidase inhibitor activity, this GO :0004866 : endopeptidase inhibitor activity and also this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0031715 : C5L2 anaphylatoxin chemotactic receptor binding, this GO :0005102 : receptor binding, this GO :0005515 : protein binding, this GO :0031715 : C5L2 anaphylatoxin chemotactic receptor binding, 12266, 19562 and IDBG-643930 and ENSBTAG00000017280 and 280677, complement component 3 |