| Also known as: |
PTPN22 / PEP |
| Other names: |
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, LyP, Lymphoid phosphatase, PEP, PEST-domain phosphatase, PEST-domain phosphatase, Tyrosine-protein phosphatase non-receptor type 22, hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, lymphoid phosphatase, lymphoid-specific protein tyrosine phosphatase, non-receptor type 22 (lymphoid), non-receptor type 8, protein tyrosine phosphatase, protein tyrosine phosphatase, tyrosine-protein phosphatase non-receptor type 22, tyrosine-protein phosphatase non-receptor type 22 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
PTPN22 |
| Other gene names: |
LYP, LYP1, LYP2, LyP, PEP, PEP, PTPN22, PTPN8, PTPN8, PTPN22 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a, k |
| Clone: |
1A6 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human PTPN22 |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
pH 7, 2, PBS |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 1A6] (IgG2a, k) PTPN22 / PEP |
| Short name: |
Mouse Monoclonal [clone 1A6] (IgG2a, k) PTPN22 / PEP Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
non-receptor classification 22 (lymphoid) / PEP (Antibody to), sapiens protein tyrosine phosphatase, Mouse monoclonal [clonality 1A6] (IgG2a, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
PTPN22 and IDBG-101222 and ENSG00000134242 and 26191, PTPN22 and IDBG-634891 and ENSBTAG00000019617 and, Ptpn22 and IDBG-181952 and ENSMUSG00000027843 and 19260, kinase binding, non-receptor type 22 (lymphoid), nuclei, this GO :0004725 and protein tyrosine phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006470 and protein dephosphorylation and biological process this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0016311 and dephosphorylation and biological process this GO :0016791 and phosphatase activity and molecular function this GO :0017124 and SH3 domain binding and molecular function this GO :0019900 and kinase binding and molecular function this GO :0030217 and T cell differentiation and biological process this GO :0032817 and regulation of natural killer cell proliferation and biological process this GO :0035335 and peptidyl-tyrosine dephosphorylation and biological process this GO :0035644 and phosphoanandamide dephosphorylation and biological process this GO :0045088 and regulation of innate immune response and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050855 and regulation of B cell receptor signaling pathway and biological process this GO :0050856 and regulation of T cell receptor signaling pathway and biological process this GO :0050860 and negative regulation of T cell receptor signaling pathway and biological process this GO :0050868 and negative regulation of T cell activation and biological process, this GO :0004725 : protein tyrosine phosphatase activity, this GO :0004725 : protein tyrosine phosphatase activity and also this GO :0005515 : protein binding and also this GO :0016791 : phosphatase activity and also this GO :0017124 : SH3 domain binding and also this GO :0019900 : kinase binding, this GO :0005515 : protein binding, this GO :0016791 : phosphatase activity, this GO :0017124 : SH3 domain binding, this GO :0019900 : kinase binding, protein tyrosine phosphatase |
| Identity: |
9652 |
| Gene: |
PTPN22 |
More about : PTPN22 |
| Long gene name: |
non-receptor type 22 , protein tyrosine phosphatase |
| Synonyms gene: |
PTPN8 |
| Synonyms gene name: |
non-receptor type 22 (lymphoid) , non-receptor type 8 protein tyrosine phosphatase, protein tyrosine phosphatase |
| Synonyms: |
Lyp Lyp1 Lyp2 |
| Locus: |
1p13, 2 |
| Discovery year: |
1999-11-26 |
| GenBank acession: |
AF001846 |
| Entrez gene record: |
26191 |
| Pubmed identfication: |
10068674 1373816 |
| RefSeq identity: |
NM_015967 |
| Classification: |
Protein tyrosine phosphatases, non-receptor type |
| Havana BLAST/BLAT: |
OTTHUMG00000011936 |