| Also known as: |
CDH2 / N Cadherin |
| Other names: |
CD_antigen: CD325, CDw325, Cadherin-2, N-cadherin, N-cadherin (neuronal), N-cadherin (neuronal), N-cadherin 1, Neural cadherin, cadherin 2, cadherin 2, cadherin-2, calcium-dependent adhesion protein, neural cadherin, neural-cadherin, neuronal, type 1, cadherin-2 preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CDH2 |
| Other gene names: |
CD325, CDH2, CDHN, CDHN, CDw325, N-cadherin, NCAD, NCAD, CDH2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
5D5 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human CDH2 |
| Purification method: |
Ascites |
| Form/Appearance: |
0, 03% sodium azide, Ascitic fluid |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
ELISA (EIA), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 5D5] (IgG1) CDH2 / N Cadherin |
| Short name: |
Mouse Monoclonal [clone 5D5] (IgG1) CDH2 / N Cadherin Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
N-cadherin (neuronal) / N Cadherin (Antibody to), classification 1, sapiens cadherin 2, Mouse monoclonal [clonality 5D5] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD325 and CDHN and CDw325 and NCAD, CDH2 and IDBG-1873 and ENSG00000170558 and 1000, CDH2 and IDBG-643792 and ENSBTAG00000021190 and 281062, Cdh2 and IDBG-129545 and ENSMUSG00000024304 and 102637155, Cell surfaces, N-cadherin (neuronal), gamma-catenin binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005912 and adherens junction and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0005916 and fascia adherens and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007157 and heterophilic cell-cell adhesion and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0014704 and intercalated disc and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0016339 and calcium-dependent cell-cell adhesion and biological process this GO :0016342 and catenin complex and cellular component this GO :0016477 and cell migration and biological process this GO :0019903 and protein phosphatase binding and molecular function this GO :0030027 and lamellipodium and cellular component this GO :0034329 and cell junction assembly and biological process this GO :0034332 and adherens junction organization and biological process this GO :0042692 and muscle cell differentiation and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045202 and synapse and cellular component this GO :0045216 and cell-cell junction organization and biological process this GO :0045294 and alpha-catenin binding and molecular function this GO :0045295 and gamma-catenin binding and molecular function this GO :0048514 and blood vessel morphogenesis and biological process this GO :0051146 and striated muscle cell differentiation and biological process this GO :0051149 and positive regulation of muscle cell differentiation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process, this GO :0005509 : calcium ion binding, this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0008013 : beta-catenin binding and also this GO :0019903 : protein phosphatase binding and also this GO :0045294 : alpha-catenin binding and also this GO :0045295 : gamma-catenin binding, this GO :0005515 : protein binding, this GO :0008013 : beta-catenin binding, this GO :0019903 : protein phosphatase binding, this GO :0045294 : alpha-catenin binding, this GO :0045295 : gamma-catenin binding, type 1, 12558, cadherin 2 |
| Identity: |
1759 |
| Gene: |
CDH2 |
More about : CDH2 |
| Long gene name: |
cadherin 2 |
| Synonyms gene: |
NCAD |
| Synonyms gene name: |
N-cadherin (neuronal) , cadherin 2, type 1 |
| Synonyms: |
CDHN CD325 |
| Synonyms name: |
N-cadherin |
| Locus: |
18q12, 1 |
| Discovery year: |
1991-09-13 |
| GenBank acession: |
S42303 |
| Entrez gene record: |
1000 |
| Pubmed identfication: |
2384753 7731968 2216790 |
| RefSeq identity: |
NM_001792 |
| Classification: |
Type I classical cadherins CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000059940 |